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拉贾斯坦邦西南部一家三级医疗中心的儿童期白癜风发病模式

Pattern of Childhood Onset Vitiligo at a Tertiary Care Centre in South- West Rajasthan.

作者信息

Kayal Ashu, Gupta Lalit K, Khare Ashok K, Mehta Sharad, Mittal Asit, Kuldeep C M

机构信息

Department of Dermatology, Venereology and Leprology, R.N.T. Medical College, Udaipur, Rajasthan, India.

出版信息

Indian J Dermatol. 2015 Sep-Oct;60(5):520. doi: 10.4103/0019-5154.164423.

Abstract

CONTEXT

Onset of vitiligo during childhood is not uncommon but the data is limited on this subject.

AIMS

This study was planned to assess the magnitude of childhood onset vitiligo (COV) and adulthood onset vitiligo (AOV), and compare their clinical pattern.

SETTINGS AND DESIGN

A cross sectional hospital based clinical study.

MATERIALS AND METHODS

Consecutive patients with vitiligo attending the Dermatology OPD of RNT Medical College and MB Government Hospital, Udaipur, from April 2012 to September 2012 were the subjects of this study. A detailed history taking followed by general, systemic and cutaneous examination, and relevant investigations were carried out. The findings were recorded in a proforma for analysis and interpretation of data.

STATISTICAL ANALYSIS USED

Statistical analysis of data was done using chi- square and Z test.

RESULTS

Of the 295 patients seen during the study period, 109 (36.95%) were patients with COV while 186 (63.05%) had AOV; the COV: AOV ratio being 1: 1.71. Amongst COV patients, females (65/109; 59.63%) outnumbered males (44/109; 40.37%). Maximum (51; 46.79%) patients of COV had onset of their disease on head and neck, out of which eyelid was the initial site of lesion in 29 (26.61%) patients. None of COV patients had universal and isolated mucosal vitiligo.

CONCLUSIONS

Female predominance, affection of eyelids as initial site, and less frequent mucosal involvement in COV were the clinical features different from AOV.

摘要

背景

白癜风在儿童期发病并不罕见,但关于这一主题的数据有限。

目的

本研究旨在评估儿童期发病白癜风(COV)和成年期发病白癜风(AOV)的发病率,并比较它们的临床模式。

设置与设计

一项基于医院的横断面临床研究。

材料与方法

本研究的对象为2012年4月至2012年9月在乌代布尔RNT医学院和MB政府医院皮肤科门诊就诊的连续性白癜风患者。详细询问病史,随后进行全身、系统和皮肤检查,并进行相关检查。检查结果记录在表格中,用于数据分析和解读。

所用统计分析方法

采用卡方检验和Z检验对数据进行统计分析。

结果

在研究期间就诊的295例患者中,109例(36.95%)为儿童期发病白癜风患者,186例(63.05%)为成年期发病白癜风患者;COV与AOV的比例为1∶1.71。在儿童期发病白癜风患者中,女性(65/109;59.63%)多于男性(44/109;40.37%)。儿童期发病白癜风患者中,最多(51例;46.79%)发病部位在头颈部,其中29例(26.61%)患者最初病变部位为眼睑。儿童期发病白癜风患者均无泛发型和孤立性黏膜白癜风。

结论

女性居多、以眼睑为初始发病部位以及儿童期发病白癜风患者黏膜受累较少是与成年期发病白癜风不同的临床特征。

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本文引用的文献

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Childhood vitiligo.儿童白癜风。
Indian J Dermatol Venereol Leprol. 2012 Jan-Feb;78(1):30-41. doi: 10.4103/0378-6323.90944.
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Vitiligo in children.儿童白癜风
Pediatr Dermatol. 2007 Nov-Dec;24(6):666. doi: 10.1111/j.1525-1470.2007.00565.x.
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The relationship between family medical history and childhood vitiligo.家族病史与儿童白癜风之间的关系。
J Am Acad Dermatol. 2006 Aug;55(2):238-44. doi: 10.1016/j.jaad.2006.02.027. Epub 2006 May 18.
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Profile of childhood vitiligo in China: an analysis of 541 patients.中国儿童白癜风概况:541例患者分析
Pediatr Dermatol. 2006 Mar-Apr;23(2):114-6. doi: 10.1111/j.1525-1470.2006.00192.x.

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