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新胆固醇指南在韩国成年糖尿病患者中的应用。

Application of New Cholesterol Guidelines to the Korean Adult Diabetic Patients.

作者信息

Kim Bu Kyung, Kim Hyeon Chang, Ha Kyoung Hwa, Kim Dae Jung

机构信息

Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.

Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea.

出版信息

J Korean Med Sci. 2015 Nov;30(11):1612-7. doi: 10.3346/jkms.2015.30.11.1612. Epub 2015 Oct 16.

Abstract

The American College of Cardiology and the American Heart Association (ACC/AHA) 2013 joint guidelines for the treatment of hypercholesterolemia expand the indications for statin therapy. This study was performed to estimate the numbers of diabetic patients indicated for statin therapy according to the Third Adult Treatment Panel (ATP-III) of the National Cholesterol Education Program guidelines and the new ACC/AHA guidelines in Korea. We analyzed the data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2012. Patients with diabetes over 30 yr of age were analyzed by the two guidelines. Of the total 1,975 diabetic patients, only 377 (19.1%) were receiving drugs for dyslipidemia. Among 1,598 patients who had not taken any medications for dyslipidemia, 65.6% would be indicated for statin therapy according to the ATP-III guidelines. When we apply the new guidelines, 94.3% would be eligible for statin therapy. Among the total diabetic patients, the new guidelines, compared with the ATP-III guidelines, increase the number eligible for statin therapy from 53.1% to 76.2%. The new guidelines would increase the indication for statin therapy for most diabetic patients. At present, many diabetic patients do not receive appropriate statin therapy. Therefore efforts should be made to develop the Korean guidelines and to ensure that more diabetic patients receive appropriate statin therapy.

摘要

美国心脏病学会和美国心脏协会(ACC/AHA)2013年高胆固醇血症治疗联合指南扩大了他汀类药物治疗的适应证。本研究旨在根据美国国家胆固醇教育计划指南的第三次成人治疗专家组(ATP-III)以及韩国新的ACC/AHA指南,估算适合接受他汀类药物治疗的糖尿病患者数量。我们分析了2010 - 2012年韩国国家健康与营养检查调查(KNHANES)的数据。采用这两个指南对30岁以上的糖尿病患者进行分析。在总共1975例糖尿病患者中,只有377例(19.1%)正在接受血脂异常治疗药物。在1598例未服用任何血脂异常治疗药物的患者中,根据ATP-III指南,65.6%的患者适合接受他汀类药物治疗。若应用新指南,94.3%的患者符合他汀类药物治疗条件。在所有糖尿病患者中,与ATP-III指南相比,新指南使适合接受他汀类药物治疗的患者数量从53.1%增至76.2%。新指南将增加大多数糖尿病患者接受他汀类药物治疗的适应证。目前,许多糖尿病患者未接受适当的他汀类药物治疗。因此,应努力制定韩国的指南,并确保更多糖尿病患者接受适当的他汀类药物治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d780/4630477/165347d4b014/jkms-30-1612-g001.jpg

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