de Lange Titia
Laboratory for Cell Biology and Genetics, The Rockefeller University , New York, NY, USA.
Front Genet. 2015 Oct 20;6:321. doi: 10.3389/fgene.2015.00321. eCollection 2015.
About a decade ago, I proposed that t-loops, the lariat structures adopted by many eukaryotic telomeres, could explain how the transition from circular to linear chromosomes was successfully negotiated by early eukaryotes. Here I reconsider this loopy hypothesis in the context of the idea that eukaryotes evolved through a period of genome invasion by Group II introns.
大约十年前，我提出t环，即许多真核生物端粒所采用的套索状结构，可以解释早期真核生物是如何成功完成从环状染色体到线性染色体的转变的。在此，我结合真核生物通过II类内含子基因组入侵时期进化而来这一观点，重新审视这一套索状假说。
