松果体区乳头状肿瘤的临床及影像学长期随访
Papillary tumor of the pineal region with extended clinical and radiologic follow-up.
作者信息
Shakir Hakeem J, Qiu Jingxin, Prasad Dheerendra, Mechtler Laszlo L, Fenstermaker Robert A
机构信息
Department of Neurosurgery, Roswell Park Cancer Institute, University at Buffalo, State University of New York, Buffalo, NY, USA ; Department of Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
Department of Pathology, Roswell Park Cancer Institute, University at Buffalo, State University of New York, Buffalo, NY, USA.
出版信息
Surg Neurol Int. 2015 Oct 7;6(Suppl 18):S451-4. doi: 10.4103/2152-7806.166782. eCollection 2015.
BACKGROUND
Papillary tumor of the pineal region (PTPR) is a rare neoplasm with only anecdotal data to guide the treatment. Results of treatment with surgery, radiation therapy, and chemotherapy have been reported to have varying degrees of success. Here we report a patient with a PTPR, who underwent subtotal resection, gamma knife stereotactic radiosurgery, and adjuvant temozolomide chemotherapy.
CASE DESCRIPTION
During 9 years of clinical and radiographic follow-up, the patient has had regression of residual tumor and remains asymptomatic.
CONCLUSION
When gross total resection of a PTPR is not possible, treatment with gamma knife stereotactic radiosurgery and temozolomide chemotherapy may provide long-term tumor control.
背景
松果体区乳头状瘤（PTPR）是一种罕见肿瘤，仅有零星数据可用于指导治疗。据报道，手术、放射治疗和化疗的治疗结果有不同程度的成功。在此，我们报告一名患有PTPR的患者，其接受了次全切除、伽玛刀立体定向放射外科治疗和辅助替莫唑胺化疗。
病例描述
在9年的临床和影像学随访中，该患者残留肿瘤消退，且仍无症状。
结论
当无法对PTPR进行全切除时，伽玛刀立体定向放射外科治疗和替莫唑胺化疗可能提供长期的肿瘤控制。
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