Schweitzer I, Tiller J, Maguire K, Davies B
Department of Psychiatry, University of Melbourne, Victoria, Australia.
Int J Clin Pharmacol Res. 1989;9(2):111-7.
A double-blind controlled study of moclobemide and diazepam in patients with atypical depression showed both to be effective antidepressants and anxiolytics. Statistical comparison showed diazepam to be significantly better than moclobemide at week 4. However, by week 8 there was no significant difference between the two drugs for depression scores although diazepam was a significantly better anxiolytic. Side-effects were minimal, and the most common side-effects emerging for both drugs were sleep disturbance and physical tiredness.
一项针对非典型抑郁症患者的吗氯贝胺与地西泮的双盲对照研究表明，两者均为有效的抗抑郁药和抗焦虑药。统计学比较显示，在第4周时地西泮明显优于吗氯贝胺。然而，到第8周时，尽管地西泮作为抗焦虑药明显更有效，但两种药物在抑郁评分上没有显著差异。副作用极小，两种药物最常见的副作用是睡眠障碍和身体疲劳。
