Marine Compounds and Cancer: Where Do We Stand?
作者信息
Dyshlovoy Sergey A, Honecker Friedemann
出版信息
Mar Drugs. 2015 Sep;13(9):5657-65. doi: 10.3390/md13095657. Epub 2015 Sep 2.
Abstract
摘要
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Xyloketal B suppresses glioblastoma cell proliferation and migration in vitro through inhibiting TRPM7-regulated PI3K/Akt and MEK/ERK signaling pathways.木酮糖酮醇B通过抑制瞬时受体电位通道M7（TRPM7）调节的磷脂酰肌醇-3激酶（PI3K）/蛋白激酶B（Akt）和丝裂原活化蛋白激酶/细胞外信号调节激酶（MEK/ERK）信号通路，在体外抑制胶质母细胞瘤细胞的增殖和迁移。
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