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高血压患者在高原暴露期间是否应调整其降压药物?

[Should hypertensive patients adapt their antihypertensive drugs during high altitude exposure?].

作者信息

Wuerzner G, Allemann Y

出版信息

Rev Med Suisse. 2015 Sep 9;11(485):1645-7.

Abstract

High altitude exposure during leisure time is becoming more and more frequent. Due to the high prevalence of hypertension in the general population, high altitude exposure in hypertensive patients may not be uncommon. The increase in blood pressure with altitude has been confirmed by ambulatory blood pressure measurement in normotensive as well as in hypertensive patients. Compared to a placebo, most hypertensive drugs keep their blood pressure lowering effect up to a certain altitude. It is recommended that hypertensive patients measure their blood pressure during high altitude, exposure and plan a possible adaptation of treatment with their physician before their sojourn.

摘要

休闲时间的高海拔暴露正变得越来越频繁。由于普通人群中高血压的高患病率,高血压患者的高海拔暴露可能并不罕见。通过动态血压测量已证实,无论是血压正常者还是高血压患者,血压都会随着海拔升高而升高。与安慰剂相比,大多数降压药在一定海拔高度内仍能保持其降压效果。建议高血压患者在高海拔暴露期间测量血压,并在旅居前与医生规划可能的治疗调整方案。

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