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地中海饮食是否是西方国家老年人保持认知功能和降低痴呆风险的可行方法?新的见解和未来方向。

Is the Mediterranean diet a feasible approach to preserving cognitive function and reducing risk of dementia for older adults in Western countries? New insights and future directions.

机构信息

School of Psychology, Social Work and Social Policy, University of South Australia, Adelaide, Australia; Alliance for Research in Exercise, Nutrition and Activity (ARENA), Australia.

School of Psychology, Social Work and Social Policy, University of South Australia, Adelaide, Australia; Alliance for Research in Exercise, Nutrition and Activity (ARENA), Australia.

出版信息

Ageing Res Rev. 2016 Jan;25:85-101. doi: 10.1016/j.arr.2015.10.005. Epub 2015 Nov 2.

Abstract

The rise in the ageing population has resulted in increased incident rates of cognitive impairment and dementia. The subsequent financial and societal burden placed on an already strained public health care system is of increasing concern. Evidence from recent studies has revealed modification of lifestyle and dietary behaviours is, at present, the best means of prevention. Some of the most important findings, in relation to the Mediterranean diet (MedDiet) and the contemporary Western diet, and potential molecular mechanisms underlying the effects of these two diets on age-related cognitive function, are discussed in this review. A major aim of this review was to discuss whether or not a MedDiet intervention would be a feasible preventative approach against cognitive decline for older adults living in Western countries. Critical appraisal of the literature does somewhat support this idea. Demonstrated evidence highlights the MedDiet as a potential strategy to reduce cognitive decline in older age, and suggests the Western diet may play a role in the aetiology of cognitive decline. However, strong intrinsic Western socio-cultural values, traditions and norms may impede on the feasibility of this notion.

摘要

人口老龄化的增加导致认知障碍和痴呆症的发病率上升。这给已经紧张的公共医疗保健系统带来了越来越大的财政和社会负担,这令人越发担忧。最近的研究证据表明,目前改变生活方式和饮食行为是预防的最佳手段。本综述讨论了与地中海饮食(MedDiet)和当代西方饮食相关的一些最重要的发现,以及这两种饮食对与年龄相关的认知功能的潜在分子机制。本综述的主要目的之一是讨论对于生活在西方国家的老年人来说,地中海饮食干预是否是一种可行的预防认知能力下降的方法。对文献的批判性评价在某种程度上支持了这一观点。有证据表明,地中海饮食是减少老年人认知能力下降的一种潜在策略,并表明西方饮食可能在认知能力下降的病因学中发挥作用。然而,强烈的内在西方社会文化价值观、传统和规范可能会阻碍这一观念的可行性。

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