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改良全层阶梯式睑裂切开术治疗东亚地区甲状腺眼病相关上睑退缩

Modified Full Thickness Graded Blepharotomy for Upper Eyelid Retraction Associated With Thyroid Eye Disease in East Asians.

作者信息

Lee Joonsik, Lee Hwa, Park Minsoo, Baek Sehyun

机构信息

From the *Department of Ophthalmology, Korea University College of Medicine, Seoul; and †Department of Ophthalmology, KEPCO Medical Center, Seoul, Korea.

出版信息

Ann Plast Surg. 2016 Dec;77(6):592-596. doi: 10.1097/SAP.0000000000000656.

Abstract

PURPOSE

To evaluate the functional and cosmetic outcomes of modified full thickness graded blepharotomy when used for East Asian patients with upper eyelid retraction of thyroid eye disease (TED).

METHOD

Medical records of each patient who underwent modified full-thickness blepharotomy at Korea University Guro Hospitals from January 2009 to February 2014 to correct upper eyelid retraction resulting from TED were retrospectively reviewed.

RESULTS

Modified full-thickness graded blepharotomies were performed on 22 eyelids of 18 patients. The most common preoperative upper eyelid retraction-associated symptom was asymmetry of the upper eyelid (14 patients, 77.7%) followed by discomfort (10 patients, 55.5%), photophobia (5 patients, 27.7%), and epiphora (4 patients, 22.2%). Most preoperative symptoms improved after blepharotomy (Table 1). Preoperatively, upper eyelid retraction (MRD1; midpupil marginal reflex distance) ranged from 2.3 mm to 6.8 mm (mean, 5.23 ± 0.89) in 22 lids; postoperatively, lid retraction significantly decreased to 3.26 ± 1.23 mm (P = 0.03 by independent t test) (Table 2). Lid retraction was divided into 3 groups according to severity; a severe group (5 eyelids, 27.7%), a moderate group (14 eyelids, 63.6%), and a mild group (3 eyelids, 13.6%). The MRD1 improved regardless of severity (P = 0.03 in the severe group, P = 0.02 in the moderate group, and P = 0.04 in the mild group by independent t test). The MRD1 improvement did not differ significantly among groups (P = 0.08 by Pearson χ t test). At 6 months postoperatively, the midpupil marginal reflex distance was the perfect height in 13 of 22 lids (59.0%), with a mean reduction of 3 mm, whereas 7 of 22 eyelids (31.8%) were at acceptable height and 2 eyelids (9.0%) showed failure. Overall, 18 eyelids (90.9%) exhibited objectively satisfactory results (perfect or acceptable) at 6 months after surgery (Table 3).

CONCLUSIONS

Modified graded full thickness eyelid blepharotomy is a reliable and safe method for upper eyelid lengthening for East Asian patients with upper eyelid retraction of TED that offers excellent functional and cosmetic results.

摘要

目的

评估改良全层分次睑裂切开术用于东亚甲状腺眼病(TED)上睑退缩患者的功能和美容效果。

方法

回顾性分析2009年1月至2014年2月在韩国大学古罗医院接受改良全层睑裂切开术以矫正TED所致上睑退缩的每位患者的病历。

结果

对18例患者的22只眼睑进行了改良全层分次睑裂切开术。术前最常见的上睑退缩相关症状是上睑不对称(14例患者,77.7%),其次是不适感(10例患者,55.5%)、畏光(5例患者,27.7%)和溢泪(4例患者,22.2%)。睑裂切开术后大多数术前症状得到改善(表1)。术前,22只眼睑的上睑退缩(MRD1;瞳孔中点边缘反射距离)范围为2.3毫米至6.8毫米(平均,5.23±0.89);术后,睑退缩显著降至3.26±1.23毫米(独立t检验,P = 0.03)(表2)。根据严重程度将睑退缩分为3组;重度组(5只眼睑,27.7%)、中度组(14只眼睑,63.6%)和轻度组(3只眼睑,13.6%)。无论严重程度如何,MRD1均有改善(重度组独立t检验P = 0.03,中度组P = 0.02,轻度组P = 0.04)。各组间MRD1改善情况差异无统计学意义(Pearson χ t检验,P = 0.08)。术后6个月时,22只眼睑中有13只(59.0%)的瞳孔中点边缘反射距离达到理想高度,平均降低3毫米,而22只眼睑中有7只(31.8%)处于可接受高度,2只眼睑(9.0%)效果不佳。总体而言,术后6个月时18只眼睑(90.9%)呈现出客观满意的结果(理想或可接受)(表3)。

结论

改良分次全层眼睑睑裂切开术是一种可靠且安全的方法,可用于东亚TED上睑退缩患者的上睑延长,能提供出色的功能和美容效果。

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