Elner Victor M, Hassan Adam S, Frueh Bartley R
Department of Ophthalmology, University of Michigan, Ann Arbor, USA.
Trans Am Ophthalmol Soc. 2003;101:67-73; discussion 73-5.
A chief morbidity of Graves' eye disease (GED) is upper lid retraction that results in exposure keratopathy and cosmetic deformity. This study was conducted to assess the efficacy of graded anterior blepharotomy to treat upper lid retraction.
Fifty eyelids of 32 patients with GED-associated upper lid retraction causing symptomatic ocular exposure were treated with graded, transcutaneous, full-thickness, anterior blepharotomy. Preoperative and postoperative ocular exposure symptoms, upper lid position, lagophthalmos, and keratopathy were compared.
At an average of 8.5 +/- 8.1 months (range, 2 to 35 months) follow-up, more than 90% of preoperative symptoms resolved or improved. Upper eyelid position (P < .00001), lagophthalmos (P < .0001), and keratopathy (P < .01) were significantly improved. Mild contour abnormalities (all < or = 1 mm) occurred in 7 of 50 eyelids. Eyelid crease recession or asymmetry occurred in 4 of 22 patients with postoperative lid crease measurements. Complications of ptosis, wound dehiscence, and full-thickness hole each occurred once. The average time for performing the procedure was 31.5 +/- 8.9 minutes per eyelid.
Graded anterior blepharotomy for upper lid retraction is a safe and highly effective surgical treatment for symptomatic GED-associated upper eyelid retraction. This technique achieves excellent functional and cosmetic outcomes.
格雷夫斯眼病(GED)的主要发病症状是上睑退缩,可导致暴露性角膜病变和外观畸形。本研究旨在评估分级前路睑裂切开术治疗上睑退缩的疗效。
对32例因GED相关上睑退缩导致有症状性眼部暴露的患者的50只眼睑进行分级、经皮、全层、前路睑裂切开术治疗。比较术前和术后的眼部暴露症状、上睑位置、眼睑闭合不全和角膜病变情况。
平均随访8.5±8.1个月(范围2至35个月),超过90%的术前症状得到缓解或改善。上睑位置(P<.00001)、眼睑闭合不全(P<.0001)和角膜病变(P<.01)均有显著改善。50只眼睑中有7只出现轻度外形异常(均≤1mm)。在22例术后测量睑裂的患者中,有4例出现睑裂退缩或不对称。上睑下垂、伤口裂开和全层缺损并发症各发生1次。该手术平均每只眼睑的操作时间为31.5±8.9分钟。
分级前路睑裂切开术治疗上睑退缩是一种安全且高效的手术治疗方法,可以有效治疗有症状的GED相关上睑退缩。该技术可实现出色的功能和外观效果。