Rubi Vargas María, González Lomelí Daniel, Terrazas Medina Efraín A, Peralta Peña Sandra L, Jordán Jinez Ma Lourdes, Ruiz Paloalto Ma Laura, Cupul Uicab Lea A
Estudiante de Doctorado en Ciencias de Enfermería, Universidad de Guanajuato. Departamento de Enfermería, Cuerpo Académico Ciencias de la Salud, División de Ciencias de la Salud, Universidad de Sonora..
Posgrado Integral de Ciencias Sociales, Cuerpo Académico Problemas Sociales, Universidad de Sonora..
Nutr Hosp. 2015 Oct 1;32(4):1744-51. doi: 10.3305/nh.2015.32.4.9567.
recent studies suggest that low serum levels of polyunsaturated fatty acids omega-3 are associated with a higher prevalence of depression.
to evaluate whether low consumption of Omega-3 fatty acids is associated with a higher prevalence of depressive symptoms in a sample of college students from the Northwest of Mexico, and to assess the potential effect modification by alcohol consumption.
we conducted a cross-sectional study in a sample of 706 college students (males and females) aged 18 to 24. The presence of depressive symptoms was identified with the Depression Scale of the Center for Epidemiologic Studies (CES-D), using a cutoff point of ≥ 24. The intake of omega-3 was obtained by a food frequency questionnaire validated for Mexican population. We estimated the weekly intake of alpha-linolenic fatty acid (ALA), eicosapentaenoic (EPA) and docosahexaenoic (DHA) derived from the diet in mg/g of food. The association between omega-3 from diet and the presence of depressive symptoms was assessed using logistic regression models adjusted for potential confounders.
67% of the participants were females; 16.6% were classified as having depressive symptoms. A low intake of ALA and EPA + DHA was not associated with depressive symptoms before and after adjusting for confounders. Median levels of ALA (from nuts only) were significantly lower among those with depressive symptoms compared to those without these symptoms.
in this population of Mexican college students, a low intake of omega-3 fatty acids was not associated with depressive symptoms. The potential association between nut consumption and depressive symptoms deserve more attention.
近期研究表明,血清中多不饱和脂肪酸omega-3水平较低与抑郁症患病率较高有关。
评估在墨西哥西北部的大学生样本中,omega-3脂肪酸摄入量低是否与抑郁症状患病率较高有关,并评估饮酒对其潜在的效应修正作用。
我们对706名年龄在18至24岁的大学生(男女生)进行了横断面研究。使用流行病学研究中心抑郁量表(CES-D),以≥24分为临界值来确定是否存在抑郁症状。通过一份针对墨西哥人群验证过的食物频率问卷来获取omega-3的摄入量。我们估计了从饮食中摄入的α-亚麻酸(ALA)、二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)的每周摄入量,单位为毫克/克食物。使用针对潜在混杂因素进行调整的逻辑回归模型评估饮食中omega-3与抑郁症状存在之间的关联。
67%的参与者为女性;16.6%被归类为有抑郁症状。在调整混杂因素前后,ALA和EPA + DHA的低摄入量与抑郁症状均无关联。有抑郁症状者中仅来自坚果的ALA中位数水平显著低于无这些症状者。
在这群墨西哥大学生中,omega-3脂肪酸摄入量低与抑郁症状无关。坚果消费与抑郁症状之间的潜在关联值得更多关注。