QCM-D 研究纳米粒子相互作用。
QCM-D study of nanoparticle interactions.
机构信息
Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China.
Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China; Beijing Key Lab of Fine Ceramics, Tsinghua University, Beijing 100084, China.
出版信息
Adv Colloid Interface Sci. 2016 Jul;233:94-114. doi: 10.1016/j.cis.2015.10.004. Epub 2015 Oct 14.
Quartz crystal microbalance with dissipation monitoring (QCM-D) has been proven to be a powerful research tool to investigate in situ interactions between nanoparticles and different functionalized surfaces in liquids. QCM-D can also be used to quantitatively determine adsorption kinetics of polymers, DNA and proteins from solutions on various substrate surfaces while providing insights into conformations of adsorbed molecules. This review aims to provide a comprehensive overview on various important applications of QCM-D, focusing on deposition of nanoparticles and attachment-detachment of nanoparticles on model membranes in complex fluid systems. We will first describe the working principle of QCM-D and DLVO theory pertinent to understanding nanoparticle deposition phenomena. The interactions between different nanoparticles and functionalized surfaces for different application areas are then critically reviewed. Finally, the potential applications of QCM-D in other important fields are proposed and knowledge gaps are identified.
石英晶体微天平（QCM-D）已被证明是一种强大的研究工具，可用于原位研究纳米颗粒与液体中不同功能化表面之间的相互作用。QCM-D 还可用于定量测定不同基底表面上溶液中聚合物、DNA 和蛋白质的吸附动力学，同时提供吸附分子构象的信息。本综述旨在全面概述 QCM-D 的各种重要应用，重点介绍在复杂流体系统中纳米颗粒的沉积和在模型膜上纳米颗粒的附着-脱附。我们将首先描述 QCM-D 的工作原理和与理解纳米颗粒沉积现象相关的 DLVO 理论。然后，批判性地综述了不同应用领域中不同纳米颗粒与功能化表面之间的相互作用。最后，提出了 QCM-D 在其他重要领域的潜在应用，并确定了知识空白。
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