Kukidome H, Matsuura N, Kasahara M, Ichinohe T
Department of Dental Anaesthesiology, Tokyo Dental College, Chiba, Japan.
Department of Dental Anaesthesiology, Tokyo Dental College, Chiba, Japan.
Int J Oral Maxillofac Surg. 2016 Apr;45(4):454-9. doi: 10.1016/j.ijom.2015.09.010. Epub 2015 Nov 3.
The aim of this study was to compare the analgesic effects of ropivacaine and levobupivacaine in continuous infiltration anaesthesia delivered via a multiple-hole catheter for the purpose of postoperative analgesia after iliac bone grafting. Thirty-four patients scheduled for iliac bone grafting in the maxillofacial region participated in this study. The patients were randomized to a ropivacaine group (Ropi group) and a levobupivacaine group (Levo group). After harvesting the iliac bone for grafting, a multiple-hole catheter was placed on the periosteum of the iliac bone. When surgery was completed, continuous administration was started at 4 ml/h of 0.2% ropivacaine (Ropi group) or 0.25% levobupivacaine (Levo group). Pain was evaluated in the recovery room and at 4h after surgery, as well as at 9:00 and 18:00 on postoperative days 1, 2, and 3, using a visual analogue scale. Side effects were also recorded. No significant difference in the visual analogue scale scores at rest or in motion was observed between the two groups. In addition, there were no side effects in the two groups. Both 0.2% ropivacaine and 0.25% levobupivacaine provided comparable analgesic effects in continuous infiltration anaesthesia delivered via a multiple-hole catheter after iliac bone grafting.
本研究旨在比较罗哌卡因和左旋布比卡因在经多孔导管持续浸润麻醉中对髂骨移植术后镇痛的效果。34例计划在颌面部进行髂骨移植的患者参与了本研究。患者被随机分为罗哌卡因组（罗哌组）和左旋布比卡因组（左旋组）。在采集髂骨用于移植后，将多孔导管置于髂骨骨膜上。手术结束后，以4ml/h的速度开始持续输注0.2%罗哌卡因（罗哌组）或0.25%左旋布比卡因（左旋组）。在恢复室、术后4小时以及术后第1、2和3天的9:00和18:00，使用视觉模拟量表评估疼痛情况。同时记录副作用。两组在静息或活动时的视觉模拟量表评分均无显著差异。此外，两组均未出现副作用。0.2%罗哌卡因和0.25%左旋布比卡因在髂骨移植后经多孔导管持续浸润麻醉中提供了相当的镇痛效果。
