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与药剂师-内分泌科医生协作的糖尿病强化医疗管理“调整”诊所对复杂患者的临床结局

Clinical Outcomes Associated With a Collaborative Pharmacist-Endocrinologist Diabetes Intense Medical Management "Tune Up" Clinic in Complex Patients.

作者信息

Morello Candis M, Christopher Melissa L D, Ortega Linda, Khoan John, Rotunno Taylor, Edelman Steven V, Henry Robert R, Hirsch Jan D

机构信息

UC San Diego, La Jolla, CA, USA Veterans Affairs of San Diego Healthcare System, San Diego, CA, USA

Veterans Affairs of San Diego Healthcare System, San Diego, CA, USA Academic Detailing for VACO Pharmacy Benefits Management, San Diego, CA, USA.

出版信息

Ann Pharmacother. 2016 Jan;50(1):8-16. doi: 10.1177/1060028015615586. Epub 2015 Nov 5.

Abstract

BACKGROUND

No previous studies exist examining the impact of a short-term pharmacist-endocrinologist collaborative practice model on glycemic control in complex patients.

OBJECTIVE

Evaluate outcomes associated with a PharmD-Endocrinologist Diabetes Intense Medical Management (DIMM) "tune up" clinic for complex patients.

METHODS

A retrospective cohort study of 99 patients referred to DIMM clinic versus a comparator group of 56 primary care provider (PCP) patients meeting the same criteria (adult type 2 diabetes patients, glycosylated hemoglobin [A1C] ≥ 8%, follow-up visit within 6 months) in a Veterans Affairs Medical Center. DIMM clinic used a short-term model that coupled personalized clinical care with real-time, patient-specific diabetes education during two to four 60-minute visits over 6 months. PCP patients received usual care. Primary outcome was mean A1C change after 6 months. Secondary measures included fasting blood glucose, lipids, blood pressure, weight, body mass index, and percentage of patients meeting goals.

RESULTS

Patients in each group had an average of 8 and were taking 12 to 14 medications daily. Mean A1C (%) improvement in DIMM group was significantly greater at 6 months (-2.4 [SD = 2.1] vs -0.8 [SD = 1.7]; P < 0.001), than PCP group. Percentage meeting A1C goal levels (<7%, <8%, and <9%) was significantly greater at 3 and 6 months compared with baseline in the DIMM group (P < 0.001) versus (only <8%) at 3 and 6 months compared with baseline in PCP group.

CONCLUSIONS

The DIMM clinic "tune up" model demonstrates a successful collaborative practice which helped complex diabetes patients achieve glycemic control in a 6-month period.

摘要

背景

既往尚无研究探讨短期药师 - 内分泌科医生协作实践模式对复杂患者血糖控制的影响。

目的

评估药学博士 - 内分泌科医生糖尿病强化医疗管理(DIMM)“调整”门诊对复杂患者的治疗效果。

方法

在一家退伍军人事务医疗中心,对99例转诊至DIMM门诊的患者与56例符合相同标准(成年2型糖尿病患者,糖化血红蛋白[A1C]≥8%,6个月内进行随访)的初级保健提供者(PCP)患者进行回顾性队列研究。DIMM门诊采用短期模式,在6个月内进行2至4次每次60分钟的就诊,将个性化临床护理与实时、针对患者的糖尿病教育相结合。PCP组患者接受常规护理。主要结局为6个月后平均A1C变化。次要指标包括空腹血糖、血脂、血压、体重、体重指数以及达到目标的患者百分比。

结果

每组患者平均年龄为8岁,且每日服用12至14种药物。6个月时,DIMM组的平均A1C(%)改善幅度显著大于PCP组(-2.4[标准差 = 2.1] vs -0.8[标准差 = 1.7];P < 0.001)。与基线相比,DIMM组在3个月和6个月时达到A1C目标水平(<7%、<8%和<9%)的百分比显著更高(P < 0.001),而PCP组在3个月和6个月时与基线相比仅<8%。

结论

DIMM门诊“调整”模式展示了一种成功的协作实践,有助于复杂糖尿病患者在6个月内实现血糖控制。

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