Nuttall Emily C, Reynolds Timothy, Kataria Ann D, Paulson Dwight, Lewis Jonathan, Straza Angela C
Department of Pharmacy, Baylor Scott & White Health, Dallas, Texas, USA.
Department of Pharmacy, Health Outcomes and Analytics, Baylor Scott & White Health, Round Rock, Texas, USA.
Proc (Bayl Univ Med Cent). 2024 Jul 23;37(5):774-780. doi: 10.1080/08998280.2024.2379195. eCollection 2024.
The value of clinical pharmacists for ambulatory internal medicine clinics is well recognized, including their role in hemoglobin A1c (HbA1c) reduction in patients with type 2 diabetes mellitus (T2DM). However, there is a lack of data evaluating the clinical impact of remote, referral-based pharmacy programs.
This multicenter, cohort, retrospective chart review study analyzed the impact of pharmacist interventions on blood glucose control in patients aged 18 years and older who were diagnosed with T2DM with an HbA1c of 8.5% or greater and referred to the clinical pharmacy team for medication evaluation. Primary care providers may have accepted or rejected pharmacist recommendations. The primary study outcome was the mean change in HbA1c from baseline to follow-up at 2 to 5 months. Secondary outcomes included appropriate use of American Diabetes Association-indicated secondary prevention and any occurrence of glycemia-related events (i.e., T2DM-related emergency room visits or hospitalizations).
At the conclusion of the study, the mean change in HbA1c from baseline to follow-up at 2 to 5 months was -2.7% and -0.6% for the accepted and rejected intervention groups, respectively (t = -2.94, = 0.0068).
The results of this study suggest that remote pharmacist intervention significantly improves blood glucose control in adults with T2DM.
临床药师在门诊内科诊所的价值已得到充分认可,包括他们在降低2型糖尿病(T2DM)患者糖化血红蛋白(HbA1c)方面的作用。然而,缺乏评估基于转诊的远程药学项目临床影响的数据。
这项多中心、队列、回顾性图表审查研究分析了药师干预对年龄在18岁及以上、被诊断为T2DM且HbA1c≥8.5%并被转诊至临床药学团队进行药物评估的患者血糖控制的影响。初级保健提供者可能接受或拒绝药师的建议。主要研究结局是从基线到2至5个月随访时HbA1c的平均变化。次要结局包括美国糖尿病协会指定的二级预防的合理使用以及任何血糖相关事件的发生(即与T2DM相关的急诊就诊或住院)。
在研究结束时,接受和拒绝干预组从基线到2至5个月随访时HbA1c的平均变化分别为-2.7%和-0.6%(t = -2.94,P = 0.0068)。
本研究结果表明,远程药师干预可显著改善成年T2DM患者的血糖控制。