Tinoco Yeny O, Azziz-Baumgartner Eduardo, Rázuri Hugo, Kasper Matthew R, Romero Candice, Ortiz Ernesto, Gomez Jorge, Widdowson Marc-Alain, Uyeki Timothy M, Gilman Robert H, Bausch Daniel G, Montgomery Joel M
U.S. Naval Medical Research Unit No. 6, Callao, Peru.
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Influenza Other Respir Viruses. 2016 Jul;10(4):301-9. doi: 10.1111/irv.12357. Epub 2016 Jan 29.
Influenza disease burden and economic impact data are needed to assess the potential value of interventions. Such information is limited from resource-limited settings. We therefore studied the cost of influenza in Peru.
We used data collected during June 2009-December 2010 from laboratory-confirmed influenza cases identified through a household cohort in Peru. We determined the self-reported direct and indirect costs of self-treatment, outpatient care, emergency ward care, and hospitalizations through standardized questionnaires. We recorded costs accrued 15-day from illness onset. Direct costs represented medication, consultation, diagnostic fees, and health-related expenses such as transportation and phone calls. Indirect costs represented lost productivity during days of illness by both cases and caregivers. We estimated the annual economic cost and the impact of a case of influenza on a household.
There were 1321 confirmed influenza cases, of which 47% sought health care. Participants with confirmed influenza illness paid a median of $13 [interquartile range (IQR) 5-26] for self-treatment, $19 (IQR 9-34) for ambulatory non-medical attended illness, $29 (IQR 14-51) for ambulatory medical attended illness, and $171 (IQR 113-258) for hospitalizations. Overall, the projected national cost of an influenza illness was $83-$85 millions. Costs per influenza illness represented 14% of the monthly household income of the lowest income quartile (compared to 3% of the highest quartile).
Influenza virus infection causes an important economic burden, particularly among the poorest families and those hospitalized. Prevention strategies such as annual influenza vaccination program targeting SAGE population at risk could reduce the overall economic impact of seasonal influenza.
需要流感疾病负担和经济影响数据来评估干预措施的潜在价值。此类信息在资源有限的环境中较为匮乏。因此,我们对秘鲁的流感成本进行了研究。
我们使用了2009年6月至2010年12月期间从秘鲁一个家庭队列中确诊的流感病例收集的数据。我们通过标准化问卷确定了自我治疗、门诊护理、急诊病房护理和住院的自我报告直接和间接成本。我们记录了发病后15天内产生的成本。直接成本包括药物、咨询、诊断费用以及交通和电话等与健康相关的费用。间接成本代表病例和护理人员在患病期间的生产力损失。我们估计了年度经济成本以及一例流感对家庭的影响。
共有1321例确诊流感病例,其中47%寻求医疗护理。确诊流感疾病的参与者自我治疗的中位数为13美元[四分位间距(IQR)5 - 26],非医疗陪同门诊疾病为19美元(IQR 9 - 34),医疗陪同门诊疾病为29美元(IQR 14 - 51),住院为171美元(IQR 113 - 258)。总体而言,预计全国流感疾病成本为8300万至8500万美元。每例流感疾病成本占最低收入四分位数家庭月收入的14%(相比最高四分位数家庭的3%)。
流感病毒感染造成了重大的经济负担,特别是在最贫困家庭和住院患者中。针对SAGE风险人群的年度流感疫苗接种计划等预防策略可降低季节性流感的总体经济影响。