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一名合并感染HIV患者的利什曼病:细针穿刺抽吸细胞学诊断

Leishmaniasis in a patient with HIV co-infection: Diagnosis on fine needle aspiration cytology.

作者信息

Bode Anjali N, Poflee Sandhya V, Pande Nandu P, Umap Pradip S

机构信息

Department of Pathology, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.

出版信息

Indian J Pathol Microbiol. 2015 Oct-Dec;58(4):563-5. doi: 10.4103/0377-4929.169020.

Abstract

Leishmaniasis is a vector borne parasitic disease caused by obligate intracellular protozoa Leishmania and is transmitted by the bite of sand fly. The disease typically presents in visceral, cutaneous and mucocutaneous forms and is endemic in some states of India. Cases with atypical presentation are seen when patient has co- infection with HIV. We report a case of Leishmaniasis occurring in a HIV seropositive expectant mother diagnosed initially on fine needle aspiration cytology. The patient was resident of non endemic area and had presented with isolated cervical lymphadenopathy and fever without spleenomegaly. Characteristic morphological features of Leishmania seen in the fine needle aspiration smears from the neck nodes were identified and definitive diagnosis of Leishmaniasis could be given. Cytological features were not suggestive of any other disease. Timely diagnosis of the disease facilitated proper management in our patient.

摘要

利什曼病是一种由专性细胞内原生动物利什曼原虫引起的媒介传播寄生虫病,通过白蛉叮咬传播。该疾病通常以内脏型、皮肤型和黏膜皮肤型出现,在印度的一些邦为地方病。当患者合并感染艾滋病毒时,会出现非典型表现的病例。我们报告一例发生在一名艾滋病毒血清阳性孕妇身上的利什曼病病例,最初通过细针穿刺细胞学检查确诊。该患者居住在非流行地区,表现为孤立性颈部淋巴结病和发热,无脾肿大。在颈部淋巴结细针穿刺涂片中发现了利什曼原虫的特征性形态学特征,从而得以明确诊断为利什曼病。细胞学特征未提示任何其他疾病。该疾病的及时诊断有助于对我们的患者进行妥善管理。

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