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HIV感染患者黏膜皮肤利什曼病的不寻常表现。

Unusual presentation of mucocutaneous leishmaniasis in HIV-infected patient.

作者信息

Bains Anupama, Vedant Deepak, Gupta Priyanka, Tegta G R

机构信息

Department of Dermatology, Venereology and Leprosy, AIIMS, Jodhpur, Rajasthan, India.

Department of Pathology, AIIMS, Jodhpur, Rajasthan, India.

出版信息

Indian J Sex Transm Dis AIDS. 2016 Jul-Dec;37(2):193-196. doi: 10.4103/0253-7184.192118.

Abstract

Leishmaniasis is caused by protozoan parasite of genus leishmania. Visceral leishmaniasis, diffuse cutaneous leishmaniasis, and atypical forms of cutaneous leishmaniasis are common in HIV-infected patients. Our patient presented with an obstructive mass in nasal cavity and was diagnosed as a case of mucocutaneous leishmaniasis. Spontaneous healing of lesions in HIV-infected patients is rare rather they are unresponsive to treatment and have frequent relapses, especially in patients with low CD4 count. However, in our patient, the lesion improved significantly after 2 months of highly active antiretroviral therapy and co-trimoxazole prophylaxis.

摘要

利什曼病由利什曼原虫属的原生动物寄生虫引起。内脏利什曼病、弥漫性皮肤利什曼病和非典型皮肤利什曼病在HIV感染患者中很常见。我们的患者表现为鼻腔内有阻塞性肿块,被诊断为皮肤黏膜利什曼病。HIV感染患者的病变很少自发愈合,相反,他们对治疗无反应且频繁复发,尤其是CD4计数低的患者。然而,在我们的患者中,经过2个月的高效抗逆转录病毒治疗和复方新诺明预防后,病变明显改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c9c/5111308/1199ae91df1e/IJSTD-37-193-g001.jpg

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