Starikov Anna, Drotman Michele, Hentel Keith, Katzen Janine, Min Robert J, Arleo Elizabeth Kagan
New York-Presbyterian/Weill Cornell, Department of Radiology, 425 East 61st Street, 9th floor, New York, NY 10065.
New York-Presbyterian/Weill Cornell, Department of Radiology, 425 East 61st Street, 9th floor, New York, NY 10065.
Clin Imaging. 2016 Jan-Feb;40(1):68-71. doi: 10.1016/j.clinimag.2015.10.001. Epub 2015 Oct 8.
To determine which modalities [2D mammography (2D), digital breast tomosynthesis (DBT), whole breast sonography (WBS)] are optimal for screening depending on breast density.
Institutional retrospective cohort study of 2013 screening mammograms (16,789), sorted by modalities and density.
Cancer detection is increased by adding WBS to 2D (P=.02) for the overall study population. Recall rate was lowest with 2D+DBT (10.2%, P<.001) and highest with 2D+DBT+WBS (23.6%, P<.001) for the overall study population as well.
Women with dense and nondense breasts benefit from reduced recall rate with the addition of DBT; however, this benefit is negated with the addition of WBS.
根据乳腺密度确定哪种检查方式[二维乳腺钼靶摄影（2D）、数字乳腺断层合成（DBT）、全乳超声检查（WBS）]最适合用于筛查。
对2013年的乳腺钼靶筛查影像（16789例）进行机构回顾性队列研究，按检查方式和密度进行分类。
对于整个研究人群，在二维乳腺钼靶摄影基础上增加全乳超声检查可提高癌症检出率（P = 0.02）。对于整个研究人群，二维乳腺钼靶摄影+数字乳腺断层合成的召回率最低（10.2%，P < 0.001），二维乳腺钼靶摄影+数字乳腺断层合成+全乳超声检查的召回率最高（23.6%，P < 0.001）。
乳腺致密和非致密的女性通过增加数字乳腺断层合成可降低召回率，但增加全乳超声检查会抵消这一益处。
