Department of Biology, Centre for Vision Research, York University, 4700 Keele Street, Toronto, Ontario M6J 1P3, Canada.
Department of Physiology and Pharmacology, Centre for Functional and Metabolic Mapping, University of Western Ontario, 1151 Richmond Street North, Ontario N6A 5B7, Canada.
Trends Neurosci. 2015 Nov;38(11):682-700. doi: 10.1016/j.tins.2015.08.009.
Attention networks comprise brain areas whose coordinated activity implements stimulus selection. This selection is reflected in spatially referenced priority maps across frontal-parietal-collicular areas and is controlled through interactions with circuits representing behavioral goals, including prefrontal, cingulate, and striatal circuits, among others. We review how these goal-providing structures control stimulus selection through long-range dynamic projection motifs. These motifs (i) combine feature-tuned subnetworks to a distributed priority map, (ii) establish endogenously controlled, long-range coherent activity at 4-10 Hz theta and 12-30 Hz beta-band frequencies, and (iii) are composed of unique cell types implementing long-range networks through disynaptic disinhibition, dendritic gating, and feedforward inhibitory gain control. This evidence reveals common circuit motifs used to coordinate attentionally selected information across multi-node brain networks during goal-directed behavior.
注意网络由大脑区域组成，其协调活动实现了刺激选择。这种选择反映在额顶叶-脑桥-皮质区域的空间参考优先级图中，并通过与代表行为目标的回路的相互作用来控制，包括前额叶、扣带回和纹状体等回路。我们回顾了这些提供目标的结构如何通过远程动态投影模式来控制刺激选择。这些模式 (i) 将特征调谐的子网组合到分布式优先级图中，(ii) 在 4-10 Hz 的 theta 和 12-30 Hz 的 beta 频带频率建立内源性控制的、远程相干活动，(iii) 由通过双突触抑制、树突门控和前馈抑制增益控制实现远程网络的独特细胞类型组成。这一证据揭示了在目标导向行为中，用于协调多节点脑网络中注意力选择信息的常见电路模式。
