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自动开放式腰椎间盘切除术与传统显微椎间盘切除术的临床及影像学结果比较:一项前瞻性随机试验

Comparison of clinical and radiological outcomes after automated open lumbar discectomy and conventional microdiscectomy: a prospective randomized trial.

作者信息

Lee Sang-Ho, Bae Jun Seok

机构信息

Department of Neurosurgery, Spine Health Wooridul Hospital Seoul, Korea.

出版信息

Int J Clin Exp Med. 2015 Aug 15;8(8):12135-48. eCollection 2015.

Abstract

OBJECTIVE

Microdiscectomy (MD) is the gold standard for surgical discectomy. As a minimally invasive discectomy, automated open lumbar discectomy (AOLD) is designed to preserve annular integrity and disc height as well as effectively remove herniated disc and degenerated disc material. However, there have been no prospective clinical studies comparing their effectiveness. The study was designed to compare clinical and radiological outcomes after AOLD with those of MD.

METHODS

Seventy-eight patients were evaluated for unilateral leg pain with the presence of disc herniation on magnetic resonance imaging (MRI) scans at a single attributable level. Sixty-two patients were enrolled; 33 patients (53%) were randomly assigned to the AOLD group and the remaining 29 patients (47%) were assigned to the MD group. Follow-up assessment was performed for 19 of the AOLD patients and 17 of the MD patients. The average follow-up period was 20 months. Clinical and functional outcomes were assessed using VAS and ODI scores. Change of disc height (DH), instability, and disc degeneration were assessed from radiographs, while Modic change and reherniation were assessed using MRI scans.

RESULTS

Postoperative VAS scores for leg pain and ODI scores for function were significantly improved in both groups. Postoperative VAS for back pain tended to decrease in the MD group but the decrease was statistically insignificant (P = 0.081). The postoperative VAS for back pain was significantly reduced in the AOLD group (P = 0.012). Patients from the MD group showed greater DH reduction than the AOLD group (P = 0.049). The MD group experienced greater disc degeneration and Modic change than the AOLD group. Follow-up MRI revealed 2 cases of reherniation in the AOLD group; 1 case was symptomatic, the other was asymptomatic.

CONCLUSIONS

AOLD showed comparable clinical and radiological outcomes to conventional MD. AOLD preserves the central disc and removes only the loose degenerative disc fragments that are the main cause of reherniation by small annulotomy. Our results suggest that preservation of the central disc prevents loss of disc height and segmental instability, which is related to postdiscectomy back pain.

摘要

目的

显微椎间盘切除术(MD)是手术椎间盘切除术的金标准。作为一种微创椎间盘切除术,自动开放式腰椎间盘切除术(AOLD)旨在保留纤维环完整性和椎间盘高度,并有效切除突出的椎间盘和退变的椎间盘组织。然而,尚无前瞻性临床研究比较它们的有效性。本研究旨在比较AOLD与MD术后的临床和影像学结果。

方法

对78例因单侧腿痛且磁共振成像(MRI)扫描显示单个责任节段椎间盘突出的患者进行评估。62例患者入选;33例患者(53%)被随机分配至AOLD组,其余29例患者(47%)被分配至MD组。对19例AOLD患者和17例MD患者进行随访评估。平均随访期为20个月。使用视觉模拟评分法(VAS)和腰椎功能障碍指数(ODI)评分评估临床和功能结果。通过X线片评估椎间盘高度(DH)变化、不稳定情况和椎间盘退变,而使用MRI扫描评估Modic改变和再突出情况。

结果

两组患者术后腿痛的VAS评分和功能的ODI评分均显著改善。MD组术后背痛的VAS评分有下降趋势,但下降无统计学意义(P = 0.081)。AOLD组术后背痛的VAS评分显著降低(P = 0.012)。MD组患者的DH降低幅度大于AOLD组(P = 0.049)。MD组比AOLD组经历了更严重的椎间盘退变和Modic改变。随访MRI显示AOLD组有2例再突出;1例有症状,另1例无症状。

结论

AOLD显示出与传统MD相当的临床和影像学结果。AOLD保留中央椎间盘,仅通过小的纤维环切开术切除作为再突出主要原因的松散退变椎间盘碎片。我们的结果表明,保留中央椎间盘可防止椎间盘高度丢失和节段不稳定,这与椎间盘切除术后背痛相关。

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