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腰椎间盘突出症标准开放椎间盘切除术后的长期临床结果、影像学表现及其相互关系。

Long-term clinical outcomes and radiological findings and their correlation with each other after standard open discectomy for lumbar disc herniation.

作者信息

Son Il-Nam, Kim Young-Hoon, Ha Kee-Yong

机构信息

Department of Orthopaedic Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

出版信息

J Neurosurg Spine. 2015 Feb;22(2):179-84. doi: 10.3171/2014.10.SPINE131126. Epub 2014 Nov 28.

Abstract

OBJECT

This retrospective study was designed to evaluate the clinical outcomes and radiological findings after open lumbar discectomy (OLD) in patients who were followed up for 10 years or longer.

METHODS

The authors classified 79 patients who had a mean age (±SD) of 53.6±13.6 years (range 30-78 years) into 4 groups according to the length of their follow-up. Patients in Group 1 were followed up for 10-14 years, in Group 2 for 15-19 years, in Group 3 for 20-24 years, and in Group 4 for more than 25 years. In all of these patients, the clinical outcomes were assessed by using patients' self-reported scores on visual analog scales (VASs) measuring back and leg pain and by using scores from the Oswestry Disability Index (ODI). In addition, 10 radiological parameters suggesting degenerative changes or instability at the operated segment were recorded at various time points and used to calculate a numeric radiological finding (NRF) score by rating a presence for each finding of spinal degeneration or instability as 1.

RESULTS

The authors observed that OLD decreased pain and disability scores in all groups. Numeric radiological findings were highest in Group 4, and a significant correlation was detected between NRFs and VAS scores of back pain (p=0.039). In this cohort, the reoperation rate was 13.9% during a mean follow-up period of 15.3 years. Clinical outcomes tended to be most favorable in Group 1, representing patients who had OLD most recently, and they tended to deteriorate in the other 3 groups, indicating some worsening of outcomes over time. Degeneration of the spine at the operated level measured with radiographic methods tended to increase over time, but some stabilization was observed. Although spinal degeneration was stable, clinical outcomes deteriorated over time.

CONCLUSIONS

This cross-sectional assessment of a retrospective cohort indicates that outcomes after OLD deteriorate over time. Increased back pain indicated a worsening of clinical outcomes, and this worsening was correlated with radiological findings of degeneration at the operated segment.

摘要

目的

本回顾性研究旨在评估接受开放性腰椎间盘切除术(OLD)且随访10年或更长时间的患者的临床结局和影像学表现。

方法

作者将79例平均年龄(±标准差)为53.6±13.6岁(范围30 - 78岁)的患者根据随访时间长度分为4组。第1组患者随访10 - 14年,第2组随访15 - 19年,第3组随访20 - 24年,第4组随访超过25年。在所有这些患者中,临床结局通过患者自我报告的视觉模拟量表(VAS)测量背痛和腿痛的评分以及Oswestry功能障碍指数(ODI)评分进行评估。此外,在不同时间点记录10个提示手术节段退变或不稳定的影像学参数,并通过将脊柱退变或不稳定的每个表现评分为1来计算影像学表现数值(NRF)评分。

结果

作者观察到OLD降低了所有组的疼痛和功能障碍评分。第4组的影像学表现数值最高,并且在NRF与背痛的VAS评分之间检测到显著相关性(p = 0.039)。在该队列中,平均随访15.3年期间的再次手术率为13.9%。临床结局在第1组中往往最有利,该组代表最近接受OLD的患者,而在其他3组中则趋于恶化,表明随着时间推移结局有所恶化。用放射学方法测量的手术节段脊柱退变倾向于随时间增加,但观察到一些稳定情况。尽管脊柱退变稳定,但临床结局随时间恶化。

结论

对一个回顾性队列的这种横断面评估表明,OLD后的结局随时间恶化。背痛增加表明临床结局恶化,并且这种恶化与手术节段退变的影像学表现相关。

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