Wu Haihu, Wang Jianwei, Lu Jiaju, Wang Yuqiu, Niu Zhihong
Department of Urology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
Urol Int. 2016;96(1):99-105. doi: 10.1159/000441424. Epub 2015 Nov 10.
To identify subgroups of patients with renal stones ≥20 mm that are more suitable for extracorporeal shock wave lithotripsy (ESWL) monotherapy.
A total of 376 patients with renal stones ≥20 mm underwent monotherapy with ESWL. The treatment outcome was evaluated after 3 months of follow-up. A stone-free status or fragmentation of stones to 4 mm or smaller was considered efficacious.
At 3 months after treatment, the overall stone-free rate was 64.4%, and the efficacy rate was 70.7%. The efficacy rate was 89.4% for patients with a residual stone surface area ≤50% of baseline after the first ESWL, while the efficacy rate was 32.4% for other patients. The efficacy was 92.2% for stones ≤400 mm2 and those with lower radiodensity, as determined by a plain (KUB) film.
For renal stones with a surface area ≤400 mm2 and a radiodensity equal to or less than that of the 12th rib as determined by a KUB film, ESWL may be considered the first line of treatment, even for stones with a diameter ≥20 mm. For large stones requiring repeat treatments, the surface area of the residual stones after the first ESWL is a predictor of the final treatment result.
识别更适合体外冲击波碎石术(ESWL)单一疗法的肾结石≥20mm患者亚组。
共有376例肾结石≥20mm患者接受了ESWL单一疗法。在随访3个月后评估治疗结果。结石清除或结石碎至4mm或更小被视为有效。
治疗后3个月,总体结石清除率为64.4%,有效率为70.7%。首次ESWL后残余结石表面积≤基线50%的患者有效率为89.4%,而其他患者有效率为32.4%。根据腹部平片(KUB)确定,结石≤400mm2且放射密度较低的患者有效率为92.2%。
对于KUB片显示表面积≤400mm2且放射密度等于或小于第12肋的肾结石,即使结石直径≥20mm,ESWL也可被视为一线治疗方法。对于需要重复治疗的大结石,首次ESWL后残余结石的表面积是最终治疗结果的预测指标。