Heng Qing-qing, Cao Liang, Li Na, Ding Gang, Wang Zhen-zhong, Xiao Wei
Zhongguo Zhong Yao Za Zhi. 2015 Jun;40(11):2206-9.
It is to observe the therapeutic action of Guizhi Fuling capsule and the combination of active ingredients on model rats with uterine leiomyoma. The hysteromyoma rats models was established in rats by loading eatrogen, to observe the effect on pathological condition of uterus, uterus wet weight, the content of estradiol and progesterone. Guizhi Fuling capsule and the combination of active ingredients remarkably decreased uterus weight, restrained the excess proliferation of the smooth muscle of uterus, decreased the estraiol and progesterone in blood serum. Guizhi Fuling capsule and the combination of active ingredients can restrain the formation of hysteromyoma in a dose-dependent manner. Perhaps the combination of active ingredients is the material foundation of antihysteromyoma.
观察桂枝茯苓胶囊及其有效成分组合对子宫肌瘤模型大鼠的治疗作用。通过给大鼠注射雌激素建立子宫肌瘤大鼠模型，观察其对子宫病理状况、子宫湿重、雌二醇和孕酮含量的影响。桂枝茯苓胶囊及其有效成分组合显著降低子宫重量，抑制子宫平滑肌过度增殖，降低血清中雌二醇和孕酮水平。桂枝茯苓胶囊及其有效成分组合能以剂量依赖方式抑制子宫肌瘤的形成。有效成分组合可能是抗子宫肌瘤的物质基础。
