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应激和干酪乳清对小鼠肠道参数的影响。

The influence of stress and cheese-whey on intestinal parameters in mice.

作者信息

Koopman J P, van den Brink M E, Scholten P M, van der Heyden M, van Schie F W, Hectors M P, Nagengast F

机构信息

Central Animal Laboratory, Catholic University, Nijmegen, The Netherlands.

出版信息

Vet Q. 1989 Jan;11(1):24-9. doi: 10.1080/01652176.1989.9694192.

Abstract

In a mouse model the effects of environmental stress on gastrointestinal parameters and the effects of cheese-whey on the changes induced by stress were studied. Mice were subjected to overcrowding, lack of bedding, overcrowding together with lack of bedding, continuous light, and housing at 30 degrees C. The influence of stress on relative caecal weight, faecal enterobacteriaceae, colonisation resistance (CR), filamentous segmented bacteria in the small intestine, fusiform bacteria in the faeces, and concentration of faecal bile acids was studied. Stress had no influence on relative caecal weight, faecal enterobacteriaceae, and faecal bile acids. Stress did decrease colonisation resistance, presence of segmented filamentous bacteria in the small intestine, and fusiform bacteria in the faeces. Cheese-whey had no positive effect on the microbiological disturbances caused by stress. The number of filamentous segmented bacteria in the small intestine and fusiforms in the faeces decreased by giving cheese-whey.

摘要

在小鼠模型中,研究了环境应激对胃肠道参数的影响以及乳清对由应激引起的变化的影响。将小鼠置于过度拥挤、缺乏垫料、过度拥挤且缺乏垫料、持续光照以及30摄氏度饲养的环境中。研究了应激对相对盲肠重量、粪便肠杆菌科、定植抗力(CR)、小肠中的丝状分节菌、粪便中的梭形菌以及粪便胆汁酸浓度的影响。应激对相对盲肠重量、粪便肠杆菌科和粪便胆汁酸没有影响。应激确实降低了定植抗力、小肠中丝状分节菌的存在以及粪便中梭形菌的数量。乳清对由应激引起的微生物紊乱没有积极作用。给予乳清后,小肠中的丝状分节菌数量和粪便中的梭形菌数量减少。

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