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血管手术后的非计划性再次手术。

Unplanned reoperations after vascular surgery.

作者信息

Kazaure Hadiza S, Chandra Venita, Mell Matthew W

机构信息

Department of Surgery, Stanford University School of Medicine, Palo Alto, Calif.

Department of Surgery, Stanford University School of Medicine, Palo Alto, Calif.

出版信息

J Vasc Surg. 2016 Mar;63(3):730-6. doi: 10.1016/j.jvs.2015.09.046. Epub 2015 Nov 6.

Abstract

OBJECTIVE

Existing literature on unplanned reoperation (UR) after vascular surgery is limited. The frequency of 30-day UR and its association with other adverse outcomes was analyzed.

METHODS

Patients who underwent vascular procedures in the American College of Surgeons National Surgical Quality Improvement Program (2012) were abstracted. UR, captured by a distinct variable now available in the data set, and its association with complications, readmissions, mortality, and failure to rescue (FTR) were analyzed using bivariate and multivariate methods.

RESULTS

Among 35,106 patients, 3545 URs were performed on 2874 patients. The overall UR rate was 10.1%. Among patients who underwent URs, approximately 80.4%, 15.8%, and 3.8% had one, two, and three or more reoperations, respectively; 39.4% of URs occurred after initial discharge. Median time to UR was 7 days but varied by procedure. Procedures with the highest UR rates were embolectomy (18.2%), abdominal bypass (14.4%), and open procedures for peripheral vascular disease (13.8%). Common indications for UR were hemorrhage, graft failure or infection, thromboembolic events, and wound complications. Patients with URs had higher rates of subsequent complications (49.9% vs 19.9%; P < .001), readmission (41.8% vs 7.0%; P < .001), and mortality (8.0% vs 2.5%; P < .001) than those not undergoing URs. FTR was more likely among patients who had a UR (13.6% vs 9.3%; P < .001); this varied within procedure groups. After multivariate adjustment, UR was independently associated with mortality in an incremental fashion (for one UR: adjusted odds ratio, 2.0; 95% confidence interval, 1.7-2.5; for two or more URs: adjusted odds ratio, 3.1; 95% confidence interval, 2.2-4.2).

CONCLUSIONS

URs within 30 days are frequent among patients undergoing vascular surgery and are associated with worse outcomes, including mortality and FTR.

摘要

目的

关于血管外科手术后非计划性再次手术(UR)的现有文献有限。分析了30天UR的发生率及其与其他不良结局的关联。

方法

提取了美国外科医师学会国家外科质量改进计划(2012年)中接受血管手术的患者资料。利用二元和多变量方法分析了UR(通过数据集中现有的一个独特变量获取)及其与并发症、再入院、死亡率和未能挽救(FTR)的关联。

结果

在35106例患者中,对2874例患者进行了3545次UR。总体UR率为10.1%。在接受UR的患者中,分别约有80.4%、15.8%和3.8%的患者进行了一次、两次以及三次或更多次再次手术;39.4%的UR发生在初次出院后。UR的中位时间为7天,但因手术不同而有所差异。UR率最高的手术是栓子切除术(18.2%)、腹部搭桥术(14.4%)以及外周血管疾病开放手术(13.8%)。UR的常见指征为出血、移植物功能衰竭或感染、血栓栓塞事件以及伤口并发症。与未接受UR的患者相比,接受UR的患者后续并发症(49.9%对19.9%;P <.001)、再入院(41.8%对7.0%;P <.001)和死亡率(8.0%对2.5%;P <.001)的发生率更高。FTR在接受UR的患者中更常见(13.6%对9.3%;P <.001);这在不同手术组中有所不同。经过多变量调整后,UR与死亡率呈递增式独立相关(一次UR:调整后的优势比为2.0;95%置信区间为1.7 - 2.5;两次或更多次UR:调整后的优势比为3.1;95%置信区间为2.2 - 4.2)。

结论

血管外科手术患者中30天内的UR很常见,并且与包括死亡率和FTR在内的更差结局相关。

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