Clinical Science Program, University of Colorado Anschutz Medical Campus, Graduate School, Colorado Clinical and Translational Sciences Institute, Aurora, Colorado; Department of Surgery, Surgical Outcomes and Applied Research Program, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, Colorado.
Department of Surgery, Surgical Outcomes and Applied Research Program, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, Colorado; Adult and Child Consortium for Health Outcomes Research and Delivery Science, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, Colorado; Department of Biostatistics and Informatics, University of Colorado Anschutz Medical Campus, Colorado School of Public Health, Aurora, Colorado.
J Surg Res. 2023 May;285:1-12. doi: 10.1016/j.jss.2022.12.016. Epub 2023 Jan 12.
Unplanned reoperation is an undesirable outcome with considerable risks and an increasingly assessed quality of care metric. There are no preoperative prediction models for reoperation after an index surgery in a broad surgical population in the literature. The Surgical Risk Preoperative Assessment System (SURPAS) preoperatively predicts 12 postoperative adverse events using 8 preoperative variables, but its ability to predict unplanned reoperation has not been assessed. This study's objective was to determine whether the SURPAS model could accurately predict unplanned reoperation.
This was a retrospective analysis of the American College of Surgeons' National Surgical Quality Improvement Program adult database, 2012-2018. An unplanned reoperation was defined as any unintended operation within 30 d of an initial scheduled operation. The 8-variable SURPAS model and a 29-variable "full" model, incorporating all available American College of Surgeons' National Surgical Quality Improvement Program nonlaboratory preoperative variables, were developed using multiple logistic regression and compared using discrimination and calibration metrics: C-indices (C), Hosmer-Lemeshow observed-to-expected plots, and Brier scores (BSs). The internal chronological validation of the SURPAS model was conducted using "training" (2012-2017) and "test" (2018) datasets.
Of 5,777,108 patients, 162,387 (2.81%) underwent an unplanned reoperation. The SURPAS model's C-index of 0.748 was 99.20% of that for the full model (C = 0.754). Hosmer-Lemeshow plots showed good calibration for both models and BSs were similar (BS = 0.0264, full; BS = 0.0265, SURPAS). Internal chronological validation results were similar for the training (C = 0.749, BS = 0.0268) and test (C = 0.748, BS = 0.0250) datasets.
The SURPAS model accurately predicted unplanned reoperation and was internally validated. Unplanned reoperation can be integrated into the SURPAS tool to provide preoperative risk assessment of this outcome, which could aid patient risk education.
非计划性再次手术是一种不理想的结果,具有相当大的风险,并且是越来越受到评估的医疗质量指标。在文献中,对于广泛的外科人群,在索引手术后,没有用于预测再次手术的术前预测模型。SURPAS(外科风险术前评估系统)使用 8 个术前变量预测 12 种术后不良事件,但尚未评估其预测非计划性再次手术的能力。本研究的目的是确定 SURPAS 模型是否能够准确预测非计划性再次手术。
这是对美国外科医师学会国家外科质量改进计划成人数据库(2012-2018 年)的回顾性分析。非计划性再次手术定义为初始计划手术后 30 天内的任何非计划手术。使用多变量逻辑回归开发了 8 变量 SURPAS 模型和包含所有可用美国外科医师学会国家外科质量改进计划非实验室术前变量的 29 变量“完整”模型,并使用判别和校准指标进行比较:C 指数(C)、Hosmer-Lemeshow 观察到的预期图和 Brier 评分(BS)。使用“训练”(2012-2017 年)和“测试”(2018 年)数据集对 SURPAS 模型进行内部时间验证。
在 5777108 名患者中,有 162387 名(2.81%)患者接受了非计划性再次手术。SURPAS 模型的 C 指数为 0.748,与完整模型的 C 指数(C=0.754)相差 99.20%。Hosmer-Lemeshow 图显示两个模型的校准均良好,BS 相似(BS=0.0264,完整;BS=0.0265,SURPAS)。训练(C=0.749,BS=0.0268)和测试(C=0.748,BS=0.0250)数据集的内部时间验证结果相似。
SURPAS 模型准确预测了非计划性再次手术,并进行了内部验证。非计划性再次手术可以整合到 SURPAS 工具中,以提供对该结果的术前风险评估,从而有助于患者的风险教育。