卵巢癌手术严重并发症的危险因素。
Risk Factors for Severe Complications in Ovarian Cancer Surgery.
机构信息
Department of Gynecology and Gynecological Oncology, University Hospital Bonn, Bonn, Germany
Department of Gynecology and Gynecological Oncology, University Hospital Bonn, Bonn, Germany.
出版信息
In Vivo. 2020 Nov-Dec;34(6):3361-3365. doi: 10.21873/invivo.12174.
UNLABELLED
Backround: Due to extensive surgical intervention for macroscopic complete cytoreduction in epithelial ovarian cancer (EOC) patients, severe complications in the postoperative course are possible.
PATIENTS AND METHODS
A total of 345 EOC patients who underwent cytoreductive surgery were retrospectively evaluated regarding risk factors for an unfavorable postoperative course. Possible pre-, intra- and postoperative risk factors were statistically analyzed performing multivariate ordinal logistic regression.
RESULTS
A total of 345 EOC patients underwent cytoreductive surgery. There were no complications in 114 patients, mild complications in 114 patients and severe complications in 117 patients. The risk factor evaluation identified age (p=0.049), smoking (p=0.032) and duration of surgery (p<0.0001) as significant factors for severe postoperative morbidity.
CONCLUSION
In EOC patients age, smoking and the duration of surgery have significant impact on the postoperative course. Only the duration of surgery can be positively influenced by a well-trained EOC team.
背景
由于上皮性卵巢癌（EOC）患者需要进行广泛的外科手术以实现宏观完全减瘤，因此术后可能会出现严重并发症。
患者和方法
回顾性评估了 345 例接受细胞减灭术的 EOC 患者，以评估术后不良病程的危险因素。通过多变量有序逻辑回归对可能的术前、术中和术后危险因素进行统计学分析。
结果
共 345 例 EOC 患者接受了细胞减灭术。114 例患者无并发症，114 例患者有轻度并发症，117 例患者有重度并发症。风险因素评估确定年龄（p=0.049）、吸烟（p=0.032）和手术持续时间（p<0.0001）是重度术后发病率的显著因素。
结论
在 EOC 患者中，年龄、吸烟和手术持续时间对术后病程有显著影响。只有手术持续时间可以通过训练有素的 EOC 团队得到积极影响。
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