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脱细胞胶原基质在阴茎增大术中的应用:沙特阿拉伯的一项初步研究。

The use of an acellular collagen matrix in penile augmentation: A pilot study in Saudi Arabia.

作者信息

Tealab Alaa A, Maarouf Aref M, Habous Mohamed, Ralph David J, Abohashem Safwat

机构信息

Elaj Medical Centre, Jeddah, Saudi Arabia ; Urology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Urology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

出版信息

Arab J Urol. 2013 Jun;11(2):169-73. doi: 10.1016/j.aju.2013.02.001. Epub 2013 Mar 22.

Abstract

OBJECTIVES

To assess the use of an acellular collagen matrix (Pelvicol, Bard Medical, Covington, GA, USA), a successful agent for reconstructive surgery, for enhancing penile girth.

PATIENTS AND METHODS

Between June and December 2011, 18 patients (mean age 24 years, range 19-38) had their penis augmented with Pelvicol; the mean (range) penile circumference was 9.2 (7-13) cm before treatment. They were divided into two groups; the first (10 patients) had a Pelvicol sheet of 8 × 12 cm inserted through a V-Y suprapubic incision and wrapped around the shaft in a bilayer under the dartos fascia, but not covering the urethra, with division of the suspensory ligament. The second group of eight patients had the Pelvicol inserted through a subcoronal degloving incision and placed in one layer. The penile circumference was measured at 6 and 12 months after surgery. Patient satisfaction at 1 year after surgery was assessed as 'poor', 'unsatisfied', 'moderately satisfied', 'highly satisfied', or 'excellent'.

RESULTS

The mean (range) increase in girth (circumference) was 2.8 (2-3.2) cm in group 1 and 1.7 (1.2-2) cm in group 2. In group 1, two patients were highly satisfied, four moderately satisfied and four unsatisfied; in group 2, three were moderately satisfied and five unsatisfied. Complications were common in both groups, with five patients in group 1 and three in group 2 developing severe penile oedema and ischaemic shaft ulcers. Removal of the graft was required in two patients in each group.

CONCLUSION

This pilot study shows that Pelvicol is not an ideal option for enhancing penile girth, and the method of placement did not apparently influence the result.

摘要

目的

评估一种脱细胞胶原基质(Pelvicol,美国佐治亚州科文顿市巴德医疗公司生产),一种在重建手术中成功应用的制剂,用于增加阴茎周长的效果。

患者与方法

2011年6月至12月期间,18例患者(平均年龄24岁,范围19 - 38岁)接受了Pelvicol阴茎增大术;治疗前阴茎平均(范围)周长为9.2(7 - 13)厘米。他们被分为两组;第一组(10例患者)通过耻骨上V - Y切口插入一张8×12厘米的Pelvicol片,在肉膜筋膜下以双层包裹阴茎体,但不覆盖尿道,并切断悬韧带。第二组8例患者通过冠状沟下脱套切口插入Pelvicol并单层放置。术后6个月和12个月测量阴茎周长。术后1年评估患者满意度,分为“差”、“不满意”、“中度满意”、“高度满意”或“优秀”。

结果

第一组阴茎周长平均(范围)增加2.8(2 - 3.2)厘米,第二组增加1.7(1.2 - 2)厘米。第一组中,2例患者高度满意,4例中度满意,4例不满意;第二组中,3例中度满意,5例不满意。两组并发症均常见,第一组5例患者、第二组3例患者出现严重阴茎水肿和阴茎体缺血性溃疡。每组各有2例患者需要取出移植物。

结论

这项初步研究表明,Pelvicol并非增加阴茎周长的理想选择,放置方法显然未对结果产生影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23ca/4442917/4e43a61935ef/fx1.jpg

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