McKay M J, Bilous A M
Department of Radiation Oncology, Westmead Hospital, Sydney, Australia.
Cancer. 1989 Jun 15;63(12):2528-31. doi: 10.1002/1097-0142(19890615)63:12<2528::aid-cncr2820631228>3.0.co;2-c.
Basaloid-squamous carcinoma, a variant of squamous cell carcinoma, has only recently been described as arising in the pharynx. The cardinal histopathologic feature, as its name suggests, is a biphasic cellular pattern of basaloid and squamous components in an intimate relationship. Major differential diagnoses include adenoid cystic, squamous, adenosquamous, and sarcomatoid carcinomas. Although the number of reported cases is small, basaloid-squamous carcinoma appears biologically virulent, with a propensity to aggressive local behavior and early regional and distant metastasis, and subsequent poor survival. The authors add a further case of basaloid-squamous carcinoma to the world literature.
基底样鳞状细胞癌是鳞状细胞癌的一种变体，直到最近才被描述为发生于咽部。顾名思义，其主要组织病理学特征是基底样和鳞状成分紧密相关的双相细胞模式。主要鉴别诊断包括腺样囊性癌、鳞状细胞癌、腺鳞癌和肉瘤样癌。尽管报告的病例数量较少，但基底样鳞状细胞癌在生物学上似乎具有侵袭性，倾向于局部侵袭性生长以及早期区域和远处转移，进而导致生存率低下。作者向世界文献中增添了另一例基底样鳞状细胞癌病例。
