Shetty Deviprasad, Subramaniam Vijayalakshmi, Herale Adarsha, Saldanha Prema, Jain Mahaveer
Yenepoya Medical College, Mangalore, India.
Contemp Oncol (Pozn). 2012;16(5):447-50. doi: 10.5114/wo.2012.31778. Epub 2012 Nov 20.
The most common type of malignancy affecting the upper aerodigestive tract is squamous cell carcinoma. Basaloid squamous cell carcinoma (BSCC) is a rarely seen, high-grade, bimorphic variant of squamous cell carcinoma, which displays distinct histological features. This entity was first described by Wain et al. in 1986. Since then, approximately 170 cases of head and neck basaloid squamous cell carcinoma have been reported. Tonsils are an uncommon site of occurrence of basaloid cell carcinoma. Only 10 cases of basaloid squamous cell carcinoma arising in the tonsils have been described in current English literature. Histopathologically, these carcinomas are characterised by the presence of a basaloid component in close association with squamous cell carcinoma. In this article, a case of BSCC of the tonsil is reported. The clinical and histopathological features of this tumour are discussed. Relevant literature has been reviewed and differential diagnosis of this tumour is discussed.
影响上呼吸道消化道的最常见恶性肿瘤类型是鳞状细胞癌。基底样鳞状细胞癌(BSCC)是一种罕见的、高级别、具有双相形态的鳞状细胞癌变体,具有独特的组织学特征。该实体于1986年由韦恩等人首次描述。从那时起,大约已报告了170例头颈部基底样鳞状细胞癌。扁桃体是基底样细胞癌不常见的发生部位。目前的英文文献中仅描述了10例起源于扁桃体的基底样鳞状细胞癌。在组织病理学上,这些癌的特征是存在与鳞状细胞癌紧密相关的基底样成分。本文报告了1例扁桃体基底样鳞状细胞癌病例。讨论了该肿瘤的临床和组织病理学特征。回顾了相关文献并讨论了该肿瘤的鉴别诊断。