a Division of Malaria Research, Proteo-Science Center , Ehime University , Matsuyama , Ehime 790-8577 , Japan.
Expert Rev Vaccines. 2016;15(1):1-3. doi: 10.1586/14760584.2016.1112744. Epub 2015 Nov 11.
Although it is more than a decade since the parasite genome information was obtained, standardized novel genome-wide selection/prioritization strategies for candidacy of malaria vaccine antigens are still sought. In the quest to systematically identify candidates, it is impossible to overemphasize the usefulness of wheat germ cell-free technology in expressing quality proteins for the post-genome vaccine candidate discovery.
尽管寄生虫基因组信息已经获得了十余年,但仍然需要标准化的新的全基因组选择/优先化策略来确定疟疾疫苗抗原的候选物。在系统地鉴定候选物的过程中,小麦胚细胞无细胞技术在表达高质量蛋白质方面的有用性,对于后基因组疫苗候选物的发现,是怎么强调都不为过的。