Martins Shirley Santos, Torres Orlando Jorge Martins, Santos Orlando José dos, Limeira Júnior Francisco de Assis, Sauaia Filho Euler Nicolau, Melo Syomara Pereira da Costa, Santos Rayan Haquim Pinheiro, Silva Vivian Brito
Hospital Universitário de Presidente Dutra, Universidade Federal do Maranhão, Sao Luis, MA, Brazil.
Department of Medicine II, UFMA, Sao Luis, MA, Brazil.
Acta Cir Bras. 2015 Oct;30(10):681-5. doi: 10.1590/S0102-865020150100000005.
To evaluate wound healing in rats by using low-level laser therapy (LLLT) associated with hydrocolloid occlusive dressing.
Forty male, adult, Wistar rats were used, distributed into four groups: LG (received 2 J/cm² of laser therapy); HG (treated with hydrocolloid); LHG (treated with 2 J/cm² of laser therapy and hydrocolloid); and the CG (treated with 1 mL of 0.9% saline). The wound was evaluated at pre-determined periods 3rd and 7th days, considering the macroscopic and histological parameters (inflammatory cells, capillary neoformation, fibroblasts, collagen formation and reepithelialization).
The LG group at seven days showed increased collagen formation, the LHG group at 3 days showed mild collagen formation. The HG group and the CG at 7 days showed complete reepithelialization.
Low-level laser therapy as well as the hydrocolloid dressing have favored the wound-healing process in rats.
通过使用与水胶体封闭敷料联合的低强度激光疗法（LLLT）来评估大鼠的伤口愈合情况。
使用40只成年雄性Wistar大鼠，分为四组：LG组（接受2 J/cm²的激光治疗）；HG组（用水胶体治疗）；LHG组（接受2 J/cm²的激光治疗和水胶体治疗）；以及CG组（用1 mL 0.9%的生理盐水治疗）。在第3天和第7天的预定时间段对伤口进行评估，考虑宏观和组织学参数（炎症细胞、毛细血管新生、成纤维细胞、胶原蛋白形成和再上皮化）。
LG组在第7天显示胶原蛋白形成增加，LHG组在第3天显示轻度胶原蛋白形成。HG组和CG组在第7天显示完全再上皮化。
低强度激光疗法以及水胶体敷料都有利于大鼠的伤口愈合过程。
