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卵母细胞冷冻保存作为预防年龄相关生育力丧失的措施。

Oocyte Cryopreservation as a Preventive Measure for Age-Related Fertility Loss.

作者信息

Cil Aylin Pelin, Turkgeldi Lale, Seli Emre

机构信息

Istanbul Memorial Hospital, Assisted Reproductive Technologies and Reproductive Genetics Center, Istanbul, Turkey.

Obstetrics and Gynecology Unit, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey.

出版信息

Semin Reprod Med. 2015 Nov;33(6):429-35. doi: 10.1055/s-0035-1567819. Epub 2015 Nov 12.

Abstract

The increased desire to achieve higher educational, career, or financial goals and not having met a suitable partner are the main reasons why women are postponing parenthood to later stages in life. Not being aware of the age-related decline in fertility and the presence of novel and effective fertility preservation strategies are contributing factors to the increased incidence of childlessness at later stages of life. Oocyte cryopreservation has recently been introduced as a means of increasing the probability of motherhood at advanced ages, should attempts at natural conception fail. It is likely to be the most effective when performed in patients younger than 35 years with a good ovarian reserve. Preconceptional counseling of women by medical professionals, education of young adolescents at schools, organization of public health campaigns, and presentation of fertility health information through the media are strategies suggested to increase public awareness on the age-related decline in fertility and avoid its possible consequences.

摘要

女性推迟生育至人生后期的主要原因是追求更高教育、职业或经济目标的愿望增强,以及尚未遇到合适伴侣。未意识到与年龄相关的生育能力下降以及新型有效生育力保存策略的存在,是导致人生后期无子女发生率增加的因素。卵母细胞冷冻保存最近已被引入,作为自然受孕尝试失败时提高高龄生育几率的一种手段。在卵巢储备良好的35岁以下患者中进行时,它可能是最有效的。医学专业人员对女性进行孕前咨询、在学校对青少年进行教育、组织公共卫生运动以及通过媒体提供生育健康信息,这些都是建议采取的策略,以提高公众对与年龄相关的生育能力下降的认识,并避免其可能产生的后果。

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