Guan Wenhui, Zhu Yinxia, Wei Qing, Wu Xiaogang, Li Li, Yan Hongjing, Yang Mengmeng, Chen Liping
Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China; Email:
Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2015 Jun;36(6):624-8.
To observe the trends on prevalence of early syphilis and HIV infection among men who had sex with men in the last six years from a HIV/AIDS counseling and testing clinic in Nanjing, and to develop relative strategies.
Men who have sex with men involved in AIDS/HIV and syphilis voluntary counseling and testing services were recruited and investigated from 2008 to 2013 in this clinic. Clients whose syphilis serologic test showed positive were determined the diagnosis by physician within the referral network from sexually transmitted diseases clinics. Demographic information on early syphilis, HIV infection or co-infection with HIV and early syphilis was described while related epidemic trend analysis was performed.
The annual numbers of men having sex with men under survey were 1 004 in 2008, 1 218 in 2009, 1 236 in 2010, 748 in 2011, 1 019 in 2012 and 1 420 in 2013. The prevalence rates of early syphilis appeared to be: 2.19% in 2008, 2.71% in 2009, 2.43% in 2010, 1.74% in 2011, 3.04% in 2012 and 2.32% in 2013, with the trend as: P > 0.05. The prevalence rates of HIV infection were 1.29% in 2008, 2.63% in 2009, 5.42% in 2010, 8.82% in 2011, 11.97% in 2012 and 10.42% in 2013, with trend as: P < 0.01. The prevalence rates of early syphilis with HIV infection increased from 0.20% in 2008 to 1.06% in 2013 (trend: P < 0.01). The proportion of HIV co-infection among men having sex with men with early syphilis infection, increased from 9.09% in 2008 to 45.45% in 2013, with trend: P < 0.01.
Early syphilis infection among men who having sex with men showed a stable trend but the number of HIV and co-infections with early syphilis and HIV increased rapidly in the last six years in Nanjing. Continued intervention strategies should target on men who have sex with men to slow down the epidemic of syphilis and HIV infection.
观察南京某艾滋病咨询检测门诊近六年男男性行为人群早期梅毒及艾滋病病毒（HIV）感染流行趋势，制定相关防控策略。
选取2008年至2013年在该门诊接受艾滋病/梅毒自愿咨询检测服务的男男性行为者进行调查。梅毒血清学检测呈阳性的患者，由性病门诊转诊网络内的医生进行诊断。描述早期梅毒、HIV感染或HIV与早期梅毒合并感染的人口学信息，并进行相关流行趋势分析。
2008年至2013年接受调查的男男性行为者人数分别为1004人、1218人、1236人、748人、1019人和1420人。早期梅毒患病率分别为：2008年2.19%，2009年2.71%，2010年2.43%，2011年1.74%，2012年3.04%，2013年2.32%，趋势分析：P>0.05。HIV感染率分别为：2008年1.29%，2009年2.63%，2010年5.42%，2011年8.82%，2012年11.97%，2013年10.42%，趋势分析：P<0.01。早期梅毒合并HIV感染率从2008年的0.20%上升至2013年的1.06%（趋势：P<0.01）。早期梅毒感染的男男性行为者中HIV合并感染比例从2008年的9.09%上升至2013年的45.45%，趋势分析：P<0.01。
南京地区男男性行为人群早期梅毒感染呈平稳态势，但近六年HIV感染及HIV与早期梅毒合并感染人数增长迅速。应持续针对男男性行为人群采取干预措施，减缓梅毒及HIV感染流行。
