Oliva Alessandra, Pavone Paola, D'Abramo Alessandra, Iannetta Marco, Mastroianni Claudio Maria, Vullo Vincenzo
Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Adv Exp Med Biol. 2016;897:85-102. doi: 10.1007/5584_2015_5007.
Implant-associated infections are difficult-to-treat conditions associated with high morbidity, mortality and length of hospitalization. They are characterized by biofilm formation on implant surface, which makes the microbiological diagnosis difficult and requires a complete device removal for the correct management. The sonication method, which is based on the application of long-wave ultrasounds radiating in a liquid medium, has been recently validated for the diagnosis of prosthetic joint infections. Additionally, this technique has been considered a potential tool in order to improve the microbiological diagnosis of infections associated with other foreign bodies, such as breast, urinary, endovascular and cerebral implants. In the present study, the application of sonication in the setting of implant-associated infections other than orthopedics will be reviewed.
植入物相关感染是难以治疗的疾病，与高发病率、死亡率和住院时间相关。其特征是在植入物表面形成生物膜，这使得微生物学诊断困难，并且需要完全移除装置才能进行正确的处理。基于在液体介质中辐射的长波超声应用的超声处理方法，最近已被验证可用于诊断人工关节感染。此外，该技术被认为是一种潜在工具，以改善与其他异物相关的感染的微生物学诊断，如乳房、泌尿、血管内和脑植入物。在本研究中，将综述超声处理在骨科以外的植入物相关感染中的应用。
