Guyenet Stephan J, Carlson Susan E
independent researcher, Edmonds, WA; and.
Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City, KS
Adv Nutr. 2015 Nov 13;6(6):660-4. doi: 10.3945/an.115.009944. Print 2015 Nov.
Linoleic acid (LA) is a bioactive fatty acid with diverse effects on human physiology and pathophysiology. LA is a major dietary fatty acid, and also one of the most abundant fatty acids in adipose tissue, where its concentration reflects dietary intake. Over the last half century in the United States, dietary LA intake has greatly increased as dietary fat sources have shifted toward polyunsaturated seed oils such as soybean oil. We have conducted a systematic literature review of studies reporting the concentration of LA in subcutaneous adipose tissue of US cohorts. Our results indicate that adipose tissue LA has increased by 136% over the last half century and that this increase is highly correlated with an increase in dietary LA intake over the same period of time.
亚油酸（LA）是一种对人体生理和病理生理具有多种作用的生物活性脂肪酸。LA是主要的膳食脂肪酸，也是脂肪组织中含量最丰富的脂肪酸之一，其在脂肪组织中的浓度反映了膳食摄入量。在美国过去的半个世纪里，随着膳食脂肪来源转向多不饱和植物油（如大豆油），膳食LA摄入量大幅增加。我们对报告美国人群皮下脂肪组织中LA浓度的研究进行了系统的文献综述。我们的结果表明，在过去的半个世纪里，脂肪组织中的LA增加了136%，并且这种增加与同期膳食LA摄入量的增加高度相关。
