Kardell M, Magnusson M, Sandborg M, Alm Carlsson G, Jeuthe J, Malusek A
Medical Radiation Physics, Department of Medical and Health Sciences and Center for Medical Image Science and Visualisation, Linköping University, SE-58185 Linköping, Sweden.
Medical Radiation Physics, Department of Medical and Health Sciences and Center for Medical Image Science and Visualisation, Linköping University, SE-58185 Linköping, Sweden Computer Vision Laboratory, Department of Electrical Engineering, Linköping University, SE-58183 Linköping, Sweden.
Radiat Prot Dosimetry. 2016 Jun;169(1-4):398-404. doi: 10.1093/rpd/ncv461. Epub 2015 Nov 12.
Advanced model-based iterative reconstruction algorithms in quantitative computed tomography (CT) perform automatic segmentation of tissues to estimate material properties of the imaged object. Compared with conventional methods, these algorithms may improve quality of reconstructed images and accuracy of radiation treatment planning. Automatic segmentation of tissues is, however, a difficult task. The aim of this work was to develop and evaluate an algorithm that automatically segments tissues in CT images of the male pelvis. The newly developed algorithm (MK2014) combines histogram matching, thresholding, region growing, deformable model and atlas-based registration techniques for the segmentation of bones, adipose tissue, prostate and muscles in CT images. Visual inspection of segmented images showed that the algorithm performed well for the five analysed images. The tissues were identified and outlined with accuracy sufficient for the dual-energy iterative reconstruction algorithm whose aim is to improve the accuracy of radiation treatment planning in brachytherapy of the prostate.
定量计算机断层扫描(CT)中基于先进模型的迭代重建算法可对组织进行自动分割,以估计成像对象的材料特性。与传统方法相比,这些算法可提高重建图像的质量和放射治疗计划的准确性。然而,组织的自动分割是一项艰巨的任务。这项工作的目的是开发和评估一种能自动分割男性骨盆CT图像中组织的算法。新开发的算法(MK2014)结合了直方图匹配、阈值处理、区域生长、可变形模型和基于图谱的配准技术,用于分割CT图像中的骨骼、脂肪组织、前列腺和肌肉。对分割图像的视觉检查表明,该算法对五张分析图像的效果良好。这些组织被准确识别和勾勒出来,足以满足双能迭代重建算法的要求,该算法旨在提高前列腺近距离放射治疗中放射治疗计划的准确性。