Tinanoff N, Manwell M A, Zameck R L, Grasso J E
School of Dental Medicine, University of Connecticut Health Center, Farmington 06032.
J Clin Periodontol. 1989 May;16(5):284-90. doi: 10.1111/j.1600-051x.1989.tb01656.x.
61 adults, with fixed or removable dental protheses, completed a 6-month double-blind trial comparing the clinical and microbial effects of brushing twice daily with either 0.22% NaF or 0.4% SnF2. Those subjects brushing with SnF2 had less gingivitis and fewer bleeding sites for both "total teeth" and "abutment teeth". Plaque scores between groups were only statistically different for the "abutment teeth". The microbial parameters, salivary S. mutans and subgingival plaque total CFU, were significantly reduced in the SnF2 group. In both treatment groups, there was a reduction over the course of the study in the number of subjects with recoverable A. actinomycetemcomitans and black pigmented bacteroides, yet there was no difference between groups.
61名佩戴固定或可摘义齿的成年人完成了一项为期6个月的双盲试验，比较每日两次使用0.22%氟化钠或0.4%氟化亚锡刷牙的临床和微生物学效果。使用氟化亚锡刷牙的受试者，无论是“全口牙齿”还是“基牙”，牙龈炎均较少，出血部位也较少。两组之间的菌斑评分仅在“基牙”方面存在统计学差异。氟化亚锡组的微生物参数，即唾液变形链球菌和龈下菌斑总菌落形成单位显著降低。在两个治疗组中，在研究过程中，可检出伴放线放线杆菌和产黑色素类杆菌的受试者数量均有所减少，但两组之间无差异。
