Sgan-Cohen H D, Gat E, Schwartz Z
Hebrew University-Hadassah, Faculty of Dental Medicine, Jerusalem, Israel.
Int Dent J. 1996 Aug;46(4):340-5.
The objectives of the present study included examining the effect of non-supervised tooth brushing with an amine fluoride/stannous fluoride (AmF/SnF2) dentifrice on gingival health of teenagers in a field trial over six months. Jerusalem high-school adolescents (246) participated in a double-blind study with a NaF dentifrice serving as control. No oral hygiene instruction or supervision was given. Examinations took place at baseline, three weeks, three months and six months. In all examinations, no differences were revealed for plaque levels. Other results indicated a consistent advantage for the AmF/SnF2 group. Gingival Index (GI) scores were significantly lower in the test group at the three month examination (GI = 0.85, compared to GI = 0.89; p = 0.036) and at the six month examination (GI = 0.72, compared to 0.78; p = 0.042) than among controls. Mean bleeding on probing scores were lower in the AmF/SnF2 than in the control group at the six month examination (0.53, compared to 0.63; p = 0.041). No side effects, including staining, were reported, nor found, among the AmF/SnF2 group. In addition to the well established caries preventive role of fluoride dentifrice, these data indicate an additional and important public health role of a AmF/SnF2 dentifrice, in preventing gingivitis.
本研究的目的包括在一项为期六个月的现场试验中,检验使用含胺氟化物/氟化亚锡(AmF/SnF₂)牙膏进行无监督刷牙对青少年牙龈健康的影响。耶路撒冷的246名高中生参与了一项双盲研究,使用含氟牙膏作为对照。未提供口腔卫生指导或监督。在基线、三周、三个月和六个月时进行检查。在所有检查中,菌斑水平均未发现差异。其他结果表明AmF/SnF₂组具有持续优势。在三个月检查时,试验组的牙龈指数(GI)得分显著低于对照组(GI = 0.85,对照组GI = 0.89;p = 0.036),在六个月检查时也是如此(GI = 0.72,对照组为0.78;p = 0.042)。在六个月检查时,AmF/SnF₂组的平均探诊出血得分低于对照组(0.53,对照组为0.63;p = 0.041)。在AmF/SnF₂组中,未报告也未发现包括染色在内的副作用。除了含氟牙膏已确立的防龋作用外,这些数据表明含AmF/SnF₂牙膏在预防牙龈炎方面具有额外且重要的公共卫生作用。