Villemin Elise, Gravel Edmond, Izard Nicolas, Filoramo Arianna, Vivien Laurent, Doris Eric
CEA, IBITECS, Service de Chimie Bioorganique et de Marquage, 91191 Gif-sur-Yvette (France).
Institut d'Electronique Fondamentale, UMR8622, CNRS-Univ. Paris-Sud, 91405 Orsay (France).
Chemistry. 2015 Dec 14;21(51):18649-53. doi: 10.1002/chem.201503741. Epub 2015 Nov 16.
A biosensor taking advantage of the optical properties of sorted carbon nanotubes has been developed. A polyfluorene polymer bearing azido groups was synthesized and used for the selective extraction of semi-conducting nanotubes from the bulk population. The resulting polymer-decorated nanotubes were then conjugated by click-chemistry to a ligand unit (biotin), and the sensing properties of the biotinylated nanotubes were investigated by photoluminescence measurements, upon interaction with the streptavidin target.
一种利用分类碳纳米管光学特性的生物传感器已被开发出来。合成了一种带有叠氮基的聚芴聚合物，并用于从大量碳纳米管中选择性提取半导体纳米管。然后通过点击化学将所得的聚合物修饰纳米管与配体单元（生物素）共轭，并通过光致发光测量研究了生物素化纳米管与链霉亲和素靶标相互作用时的传感特性。
