Bao Yuhua, Druss Benjamin G, Jung Hye-Young, Chan Ya-Fen, Unützer Jürgen
Dr. Bao and Dr. Jung are with the Department of Healthcare Policy and Research, Weill Cornell Medical College, New York City (e-mail:
Psychiatr Serv. 2016 Apr 1;67(4):418-24. doi: 10.1176/appi.ps.201400577. Epub 2015 Nov 16.
This study examined how two key process-of-care tasks of the collaborative care model (CCM) predict patient depression outcomes.
Registry data were from a large implementation of the CCM in Washington State and included 5,439 patient-episodes for patients age 18 or older with a baseline Patient Health Questionnaire-9 (PHQ-9) score of ≥10 and at least one follow-up contact with the CCM care manager within 24 weeks of initial contact. Key CCM tasks examined were at least one care manager follow-up contact within four weeks of initial contact and at least one psychiatric consultation between weeks 8 and 12 for patients not responding to treatment by week 8. Clinically significant improvement in depression symptoms was defined as achieving a PHQ-9 score of <10 or a 50% or more reduction in PHQ-9 score compared with baseline. Bivariate and multivariate (logistic and proportional hazard models) analyses were conducted to examine how fidelity with either task predicted outcomes. All analyses were conducted with the original sample and with a propensity score-matched sample.
Four-week follow-up was associated with a greater likelihood of achieving improvement in depression (odds ratio [OR]=1.63, 95% confidence interval [CI]=1.23-2.17) and a shorter time to improvement (hazard ratio=2.06, CI=1.67-2.54). Psychiatric consultation was also associated with a greater likelihood of improvement (OR=1.44, CI=1.13-1.84) but not with a shorter time to improvement. Propensity score-matched analysis yielded very similar results.
Findings support efforts to improve fidelity to the two process-of-care tasks and to include these tasks among quality measures for CCM implementation.
本研究探讨协作照护模式(CCM)的两项关键照护流程任务如何预测患者的抑郁结局。
登记数据来自华盛顿州大规模实施的CCM,包括5439例患者病程记录,患者年龄在18岁及以上,基线患者健康问卷-9(PHQ-9)评分≥10,且在初次接触后的24周内至少与CCM照护经理进行过一次随访接触。所考察的关键CCM任务包括初次接触后四周内至少有一次照护经理随访接触,以及在第8周时对治疗无反应的患者在第8至12周期间至少进行一次精神科会诊。抑郁症状的临床显著改善定义为PHQ-9评分<10,或与基线相比PHQ-9评分降低50%或更多。进行双变量和多变量(逻辑回归和比例风险模型)分析,以考察对任一任务的依从性如何预测结局。所有分析均在原始样本和倾向得分匹配样本中进行。
四周随访与抑郁改善的可能性更大相关(优势比[OR]=1.63,95%置信区间[CI]=1.23 - 2.17),且改善时间更短(风险比=2.06,CI=1.67 - 2.54)。精神科会诊也与改善的可能性更大相关(OR=1.44,CI=1.13 - 1.84),但与改善时间缩短无关。倾向得分匹配分析得出非常相似的结果。
研究结果支持努力提高对这两项照护流程任务的依从性,并将这些任务纳入CCM实施的质量指标中。