Lundberg W B, Cadman E D, Finch S C, Capizzi R L
Am J Med. 1977 Apr;62(4):636-42. doi: 10.1016/0002-9343(77)90427-2.
Leukemic infiltration of the kidneys is a very rare cause of renal failure. A woman with acute lymphoblastic leukemia presented with nonliguric renal failure and was found to have massively enlarged kidneys. The size of the kidneys was dramatically reduced through the combined effects of local radiation therapy and systemic chemotherapy. Because this rapid shrinkage of the kidneys was associated with improvement in renal function, the uremia was ascribed to leukemic infiltration. As a consequence of rapid tumor lysis in the presence of renal failure, marked hyperphosphatemia and hypocalcemia developed. The literature experience with renal failure secondary to leukemic infiltration of the kidneys is reviewed.
肾脏的白血病浸润是肾衰竭非常罕见的病因。一名急性淋巴细胞白血病女性患者出现非少尿型肾衰竭，且发现其肾脏大幅增大。通过局部放射治疗和全身化疗的联合作用，肾脏大小显著缩小。由于肾脏的这种快速缩小与肾功能改善相关，故将尿毒症归因于白血病浸润。由于在肾衰竭情况下肿瘤快速溶解，出现了明显的高磷血症和低钙血症。本文对继发于肾脏白血病浸润的肾衰竭的文献经验进行了综述。
