Davarpanah Mohammad Ali, Hosseinzadeh Farideh, Mohammadi S Saeed
Department of Infectious Diseases, Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Iran Red Crescent Med J. 2015 Oct 19;17(10):e19373. doi: 10.5812/ircmj.19373. eCollection 2015 Oct.
Paraquat is a widely used nitrogen-based herbicide which is lethal and causes multi-organ failure by accumulation in cells, which subsequently leads to death.
The present case report introduced a 25-year-old male with nausea, vomiting, and severe substernal burning sensation after incidentally ingestion of a large amount of paraquat. The treatment of the patient with antioxidants (N-acetylcysteine and vitamin E) and hemodialysis started immediately after arriving to the hospital.
Immediate and adequate use of antioxidants and hemodialysis has an undeniable and important role in survival of patients after ingestion of a large amount of paraquat.
百草枯是一种广泛使用的含氮除草剂，具有致命性，可通过在细胞内蓄积导致多器官功能衰竭，进而导致死亡。
本病例报告介绍了一名25岁男性，在意外摄入大量百草枯后出现恶心、呕吐和严重的胸骨后烧灼感。患者入院后立即开始使用抗氧化剂（N-乙酰半胱氨酸和维生素E）及血液透析进行治疗。
在大量摄入百草枯后，立即且充分地使用抗氧化剂和血液透析对患者的存活起着不可否认的重要作用。
