Pap I, Kertész J, Sági I
Orv Hetil. 1989 Apr 2;130(14):735-6.
A 26-year old woman took 4000 mg (100 tablets) of VerpamilR (Orion Pharmaceutica, Helsinki) with suicidal intestions. As a consequence of the poisoning cardiogenic shock, 3rd grade AV block and cardiac arrest occurred. The disturbance of stimulus formation and conduction was treated with a temporary pacemaker. Discussing the therapeutical possibilities it is stated that cardiovascular symptoms may be influenced successfully by Ca++ preparations (Calcium gluconicum, Calcium chloratum) and beta-receptor stimulants (isoproterenol, dopamine, orciprenalin) possibly also with glucagon.
一名26岁女性出于自杀意图服用了4000毫克(100片)维拉帕米(芬兰赫尔辛基奥立安制药公司生产)。中毒导致心源性休克、三度房室传导阻滞和心脏骤停。通过临时起搏器治疗刺激形成和传导障碍。在讨论治疗可能性时指出,心血管症状可能会被钙制剂(葡萄糖酸钙、氯化钙)和β受体兴奋剂(异丙肾上腺素、多巴胺、奥西那林)成功影响,可能还会用到胰高血糖素。