通过乌吉型三组分缩合（3CC）反应简便地微波辅助合成苯并咪唑支架。
Facile microwave-assisted synthesis of benzimidazole scaffolds via Ugi-type three-component condensation (3CC) reactions.
作者信息
Song Gui-Ting, Xu Zhi-Gang, Tang Dian-Yong, Li Shi-Qiang, Xie Zhi-Gang, Zhong Hong-Liang, Yang Zhi-Wei, Zhu Jin, Zhang Jin, Chen Zhong-Zhu
机构信息
International Academy of Targeted Therapeutics and Innovation, Chongqing University of Arts and Sciences, 319 Honghe Ave., Yongchuan, Chongqing, 402160, China.
Key Laboratory for Asymmetric Synthesis and Chiral Technology of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041, China.
出版信息
Mol Divers. 2016 May;20(2):575-80. doi: 10.1007/s11030-015-9646-7. Epub 2015 Nov 18.
Two series of fused benzimidazoles were synthesized via a facile, one-pot procedure under microwave irradiation. This procedure generated the desired products in high yields and could provide a useful synthetic platform with potential applications in medicinal chemistry.
通过微波辐射下简便的一锅法合成了两个系列的稠合苯并咪唑。该方法以高产率生成所需产物，并可为药物化学中的潜在应用提供有用的合成平台。
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