Loftus Patrick D, Elder Craig T, Russell Katie W, Spanos Stephen P, Barnhart Douglas C, Scaife Eric R, Skarda David E, Rollins Michael D, Meyers Rebecka L
Division of Pediatric Surgery, University of Utah, Primary Children's Hospital, Salt Lake City, UT, USA.
Division of Pediatric Anesthesiology, University of Utah, Primary Children's Hospital, Salt Lake City, UT, USA.
J Pediatr Surg. 2016 Jan;51(1):149-53. doi: 10.1016/j.jpedsurg.2015.10.037. Epub 2015 Oct 23.
Management of postoperative pain following repair of pectus excavatum has traditionally included thoracic epidural analgesia, narcotics, and benzodiazepines. We hypothesized that the use of intercostal or paravertebral regional blocks could result in decreased inpatient length of stay (LOS).
We conducted a retrospective cohort study of 137 patients (118 Nuss and 19 Ravitch - Nuss and Ravitch patients were analyzed separately) who underwent surgical repair of pectus excavatum with pain management via epidural, intercostal, or paravertebral analgesia from January 2009-December 2012. Measured outcomes included LOS, pain scores, benzodiazepine/narcotic requirements, emesis, professional fees, hospital cost, and total cost.
In the Nuss patients, LOS was significantly reduced in the paravertebral group (p<0.005) and the intercostal group (p<0.005) compared to the epidural group, but was paradoxically countered by a nonsignificant increase in total cost (p=0.09). While benzodiazepine doses/day was not increased in the paravertebral group (p=0.08), an increase was seen in narcotic use (p<0.005). Despite increased narcotic use, no differences were seen in emesis between epidural and paravertebral use. Compared to epidural, pain scores were higher for both intercostal and paravertebral on day one (p<0.005), but equivalent for paravertebral on day three (p=0.62). The Ravitch group was too small for detailed independent statistical analysis but followed the same overall trend seen in the Nuss patients.
Our use of paravertebral continuous infusion pain catheters for pectus excavatum repair was an effective alternative to epidural analgesia resulting in shorter LOS but not a decrease in overall cost.
传统上,漏斗胸修复术后疼痛的管理包括胸段硬膜外镇痛、使用麻醉药和苯二氮䓬类药物。我们推测,使用肋间或椎旁区域阻滞可缩短住院时间(LOS)。
我们对2009年1月至2012年12月期间接受漏斗胸手术修复并通过硬膜外、肋间或椎旁镇痛进行疼痛管理的137例患者(118例Nuss手术患者和19例Ravitch手术患者——Nuss手术和Ravitch手术患者分别进行分析)进行了一项回顾性队列研究。测量的结果包括住院时间、疼痛评分、苯二氮䓬类药物/麻醉药需求量、呕吐情况、专业费用、医院成本和总成本。
在Nuss手术患者中,与硬膜外组相比,椎旁组(p<0.005)和肋间组(p<0.005)的住院时间显著缩短,但矛盾的是,总成本出现了无统计学意义的增加(p=0.09)。虽然椎旁组苯二氮䓬类药物每日剂量未增加(p=0.08),但麻醉药使用量增加(p<0.005)。尽管麻醉药使用量增加,但硬膜外和椎旁使用时呕吐情况并无差异。与硬膜外相比,肋间和椎旁在第1天的疼痛评分更高(p<0.005),但椎旁在第3天的疼痛评分相当(p=0.62)。Ravitch手术组规模太小,无法进行详细的独立统计分析,但总体趋势与Nuss手术患者相同。
我们使用椎旁连续输注镇痛导管进行漏斗胸修复术是硬膜外镇痛的有效替代方法,可缩短住院时间,但并未降低总体成本。