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先天性疟疾:一种罕见病症。

Congenital Malaria: A Rare Entity.

作者信息

Bugvi Saima Mansoor, Ahmed Nisar

机构信息

Department of Hematology and Transfusion Medicine, Child Hospital and ICH, Lahore.

出版信息

J Coll Physicians Surg Pak. 2015 Nov;25(11):841-2.

Abstract

Congenital malaria is the presence of malarial parasites in the blood of newborns. The disease is acquired from mother either during pregnancy or perinatally at the time of birth. Congenital malaria in an endemic area can present without an obvious history of fever and parasitaemia in both mother and her infant. A case of Plasmodium vivax malaria in a 6-week infant is documented. Infant presented with pallor, jaundice and massive spleen. Laboratory tests revealed anaemia, thrombocytopenia and bilirubinemia. Peripheral smear examination revealed parasitaemia. Points favoring transplacental transmission are first born child, the presence of relatively high parasite count, gametocytemia and massive spleen. Peripheral smear examination should be done in all hospitalized patients. Prevention of malaria should be considered in all pregnant patients.

摘要

先天性疟疾是指新生儿血液中存在疟原虫。该疾病是母亲在孕期或出生时围产期传染给新生儿的。在疟疾流行地区,先天性疟疾可能在母亲及其婴儿均无明显发热和寄生虫血症病史的情况下出现。记录了一例6周龄婴儿患间日疟原虫疟疾的病例。婴儿表现为面色苍白、黄疸和脾脏肿大。实验室检查显示贫血、血小板减少和胆红素血症。外周血涂片检查发现寄生虫血症。支持经胎盘传播的因素有:头胎、寄生虫计数相对较高、配子体血症和脾脏肿大。所有住院患者均应进行外周血涂片检查。所有孕妇均应考虑预防疟疾。

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