膀胱平滑肌瘤:临床表现、评估与治疗

Bladder leiomyoma: Presentation, evaluation and treatment.

作者信息

Khater Nazih, Sakr Ghazi

机构信息

Rafik Hariri University Hospital, Division of Urology, American University of Beirut, Beirut, Lebanon.

出版信息

Arab J Urol. 2013 Mar;11(1):54-61. doi: 10.1016/j.aju.2012.11.007. Epub 2012 Dec 25.

Abstract

BACKGROUND

Bladder leiomyomas are benign mesenchymal neoplasms and very rare urinary tumours that represent <0.5% of all bladder tumours, with only 250 cases reported worldwide to date. The importance of recognising their characteristic features, leading to their correct treatment, is fundamental. Therefore, we reviewed reports of leiomyomas of the urinary bladder, their causes, clinical presentations, imaging methods and surgical management, updated to 2012.

METHODS

We retrospectively reviewed articles published in the USA, Europe and Asia, from 1953 to date, using PubMed, Medscape, Medline and the several major journals. We report areas of controversies and well-established guidelines.

RESULTS

We reviewed 36 articles that confirmed, with a high level of evidence-based medicine, that the male to female ratio is equal, the cause of bladder leiomyomas remains unknown, and their most common presentation is obstructive uropathy; endovesical tumours are the most common. Their radiological diagnosis can be made by ultrasonography, computed tomography or magnetic resonance imaging. Complete surgical resection is a very effective treatment, associated with almost no recurrence.

CONCLUSION

In symptomatic patients a complete surgical resection can give a very good outcome, with almost no recurrence.

摘要

背景

膀胱平滑肌瘤是一种良性间叶肿瘤,是非常罕见的泌尿系统肿瘤,占所有膀胱肿瘤的比例不到0.5%,迄今为止全球仅报道了250例。认识其特征对于正确治疗至关重要。因此,我们回顾了截至2012年关于膀胱平滑肌瘤的报告,包括其病因、临床表现、影像学检查方法及手术治疗。

方法

我们使用PubMed、Medscape、Medline及其他几家主要期刊,回顾了1953年至今在美国、欧洲和亚洲发表的文章。我们报告了存在争议的领域和已确立的指南。

结果

我们回顾了36篇文章,这些文章以高水平的循证医学证实,膀胱平滑肌瘤的男女比例相同,病因仍不明,最常见的表现是梗阻性尿路病;膀胱内肿瘤最为常见。其影像学诊断可通过超声、计算机断层扫描或磁共振成像做出。完整的手术切除是一种非常有效的治疗方法,几乎无复发。

结论

对于有症状的患者,完整的手术切除可取得很好的效果,几乎无复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0849/4442969/4e43a61935ef/fx1.jpg

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