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病例系列——泌尿道平滑肌瘤患者膀胱保留治疗的优先排序:三例报告及最新文献综述

Case series - Prioritizing bladder-sparing treatments in patients with urinary tract leiomyoma: A report of three cases and updated literature review.

作者信息

McNall Shannon, Park Terry, Gopal Nikhil, Spencer Evan, Vemulakonda Lakshmisree Akhila, Choudhury Muhammad, Wong Nathan Colin

机构信息

New York Medical College, Valhalla, NY, United States.

Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, United States.

出版信息

Can Urol Assoc J. 2022 Nov;16(11):E563-E568. doi: 10.5489/cuaj.7745.

DOI:10.5489/cuaj.7745
PMID:35704928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9665312/
Abstract

Urinary tract leiomyomas are rare, benign mesenchymal tumors that are traditionally treated with complete surgical excision. We present three cases of urinary tract leiomyoma - two located in the bladder and one in the ureter. Both bladder leiomyomas were treated with transurethral resection of bladder tumor (TURBT) with no evidence of recurrent disease, while the upper tract leiomyoma was managed with surveillance by patient preference, which to our knowledge, has not been previously described. The ureteral leiomyoma has remained stable at five years followup from initial diagnosis. Given the benign nature of leiomyomas and the overall low recurrence rate reported in the literature, bladder-sparing options should be emphasized when feasible, with active surveillance potentially applicable for highly select patients.

摘要

泌尿道平滑肌瘤是罕见的良性间叶组织肿瘤,传统上采用完整手术切除治疗。我们报告三例泌尿道平滑肌瘤病例,两例位于膀胱,一例位于输尿管。两例膀胱平滑肌瘤均采用经尿道膀胱肿瘤切除术(TURBT)治疗,无疾病复发证据,而上尿路平滑肌瘤根据患者意愿进行监测,据我们所知,此前尚无此类报道。输尿管平滑肌瘤自初次诊断后五年随访一直保持稳定。鉴于平滑肌瘤的良性性质以及文献报道的总体低复发率,可行时应强调保留膀胱的选择,主动监测可能适用于经过严格筛选的患者。

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本文引用的文献

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A rare cause of hydronephrosis: Leiomyoma of the ureter and a literature review.肾积水的一种罕见病因:输尿管平滑肌瘤及文献综述
Urologia. 2023 Feb;90(1):189-191. doi: 10.1177/03915603211010463. Epub 2021 Apr 19.
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Open Partial Cystectomy of Intramural Bladder Leiomyoma With Unfavorable Position: A Rare Case Report.位置不佳的膀胱壁内平滑肌瘤开放性部分膀胱切除术:1例罕见病例报告
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Bladder Leiomyoma.
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Rare case presentation of leiomyoma of bladder neck with tuberculous pelvic lymphadenitis in a young female patient.一名年轻女性患者膀胱颈部平滑肌瘤合并结核性盆腔淋巴结炎的罕见病例报告。
Urol Case Rep. 2020 Oct 5;34:101436. doi: 10.1016/j.eucr.2020.101436. eCollection 2021 Jan.
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Transvesical laparoscopy for bladder leiomyoma excision: a novel surgical technique.经膀胱腹腔镜下膀胱平滑肌瘤切除术:一种新的手术技术。
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Transurethral resection of a bladder trigone leiomyoma: a rare case report.经尿道膀胱三角区平滑肌瘤切除术:1 例罕见病例报告。
BMC Urol. 2020 Oct 7;20(1):152. doi: 10.1186/s12894-020-00722-2.
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Cystoscope-Assisted Laparoscopic Enucleation of a Large Progressive Bladder Leiomyoma.膀胱镜辅助下腹腔镜剥除巨大进行性膀胱平滑肌瘤
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European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.欧洲泌尿外科学会上尿路尿路上皮癌指南:2020 年更新版。
Eur Urol. 2021 Jan;79(1):62-79. doi: 10.1016/j.eururo.2020.05.042. Epub 2020 Jun 24.
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A large bladder leiomyoma.一个巨大的膀胱平滑肌瘤。
Urol Case Rep. 2020 Apr 15;32:101211. doi: 10.1016/j.eucr.2020.101211. eCollection 2020 Sep.
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